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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of Chlorhexidine on Denture Biofilm Accumulation

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Author(s):
de Andrade, Ingrid Machado [1] ; Cruz, Patricia C. [1] ; Silva-Lovato, Cludia H. [1] ; de Souza, Raphael F. [1] ; Monteiro Souza-Gugelmin, Maria Cristina [2] ; Oliveira Paranhos, Helena de Freitas [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Ribeirao Preto Dent Sch, Dept Dent Mat & Prosthodont, BR-14040904 Ribeirao Preto - Brazil
[2] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, Dept Clin Toxicol & Bromatol Anal, BR-14040904 Ribeirao Preto - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY; v. 21, n. 1, p. 2-6, JAN 2012.
Web of Science Citations: 17
Abstract

Purpose: Adequate denture hygiene can prevent and treat infection in edentulous patients, who are frequently elderly and have difficulty brushing their teeth. This study evaluated the efficacy of complete denture biofilm removal using a chlorhexidine solution in two concentrations: 0.12% and 2.0%. Materials and Methods: Sixty complete denture wearers participated in a trial for 21 days after receiving brushing instructions. They were distributed into three groups, according to the tested solution and regimen (n = 20): (G1) Control (daily overnight soaking in water); (G2) daily immersion at home in 0.12% chlorhexidine for 20 minutes after dinner; and (G3) a single immersion in 2.0% chlorhexidine for 5 minutes at the end of the experimental period, performed by a professional. Biofilm coverage area (%) was quantified on the internal surface of maxillary dentures at baseline and after 21 days. Afterward, the differences between initial and posttreatment results were compared by means of the Kruskal-Wallis test (a = 0.05). Results: Median values for biofilm coverage area after treatment were: (G1) 36.0%; (G2) 5.3%; and (G3) 1.4%. Differences were significant (KW = 35.25; p < 0.001), although G2 and G3 presented similar efficacy in terms of biofilm removal. Conclusions: Both chlorhexidine-based treatments had a similar ability to remove denture biofilm. Immersion in 0.12% or 2.0% chlorhexidine solutions can be used as an auxiliary method for cleaning complete dentures. (AU)