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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Co- encapsulation of Lactobacillus acidophilus with inulin or polydextrose in solid lipid microparticles provides protection and improves stability

Full text
Author(s):
Okuro, Paula K. [1] ; Thomazini, Marcelo [1] ; Balieiro, Julio C. C. [1] ; Liberal, Roberta D. C. O. [1] ; Favaro-Trindade, Carmen S. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos, Pirassununga, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Food Research International; v. 53, n. 1, p. 96-103, AUG 2013.
Web of Science Citations: 59
Abstract

The aims of this study were to produce and evaluate solid lipid microparticles (SLM) in which Lactobacillus acidophilus (La), a probiotic, was co-encapsulated with a prebiotics, either inulin (mu) or polydextrose (Poly) using spray chilling technology. Morphological, chemical, and thermal characterisation of SLMs were conducted, along with survival assays to evaluate the resistance of the probiotic to the microencapsulation process, its resistance to exposure to simulated gastric fluids (SGF) and simulated intestinal fluids (SIF), and its stability throughout storage for 120 days at -18, 7 and 22 degrees C a vacuum or with controlled relative humidity. Cell viability was not affected by the spray-chilling process. All of the microcapsules produced in the present study increased the survival rate of La exposed to SGF and SIF compared to that of free probiotic cells. Promising results were obtained when these microcapsules were stored refrigerated and frozen with a controlled relative humidity. This study indicated that combined spray chilling process, combined with the addition of a prebiotic component, specifically polydextrose is an interesting technology for the protection, delivery and improve stability of probiotics, which increases the potential of symbiotic SLMs. Scaling up the spray chilling technique will allow efficient encapsulation of probiotics in a lipid matrix. (C) 2013 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 09/11713-2 - Development of vehicles for controlled release of probiotics
Grantee:Carmen Sílvia Fávaro Trindade
Support Opportunities: Regular Research Grants
FAPESP's process: 10/13026-0 - Development, evaluation and application of symbiotic microcapsules obtained by spray chilling
Grantee:Paula Kiyomi Okuro
Support Opportunities: Scholarships in Brazil - Master