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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Histologic, Histomorphometric, and Radiographic Monitoring of Bone Healing Around In-Office-Sterilized Orthodontic Mini-implants With or Without Immediate Load: Study in Rabbit Tibiae

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Author(s):
Chibebe Catharino, Priscilla Campanatti [1] ; Dominguez, Gladys Cristina [1] ; Pinto, Jr., Decio dos Santos [2] ; Morea, Camillo [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Fac Dent, Dept Orthodont, BR-05508 Sao Paulo - Brazil
[2] Univ Sao Paulo, Fac Dent, Dept Stomatol, BR-05508 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS; v. 29, n. 2, p. 321-330, MAR-APR 2014.
Web of Science Citations: 3
Abstract

Purpose: The objective of this study was to describe bone healing around self-drilling orthodontic mini-implants (MIs), sterilized in an office with an autoclave, with or without immediate orthodontic loading. Materials and Methods: One hundred forty-four self-drilling MIs (TOMAS, Dentaurum) were inserted into the tibiae of 18 white rabbits, with full-thickness flaps elevated under general anesthesia. An immediate load (50 cN) was applied to 50% of the MIs. Two rabbits were sacrificed soon after the surgery and served as a control group. Four rabbits each were sacrificed at 15, 21, 30, or 60 days after the surgeries. Digital radiographs were obtained to measure the cortical bone thickness (CBT) around and between the implants. Sections were obtained and stained for histologic and histomorphometric analysis. Bone quantity (BQ), bone-to-implant contact (BIC), and CBT were evaluated statistically. Results: At day 0, fractures were visible in the cortical area around the MIs. At days 15 and 21, intense proliferation of woven bone followed by formation of lamellar bone was seen. After 30 days, primary bone was visible, with less proliferation activity. At day 60, primary bone in the process of remodeling into secondary bone was apparent. BQ was better with loading after 15 days and increased throughout the healing period in the loaded and unloaded groups. Loading did not influence the BIC values, which increased with healing time for loaded and unloaded implants. CBT increased in all regions, and CBT was greater around the MIs than between them except for unloaded MIs in the 15-day group. Conclusion: An immediate, light orthodontic load did not affect the bone healing process around orthodontic MIs. Osseointegration and CBT increased and were time-related. (AU)

FAPESP's process: 10/09422-7 - Histologic and histomorphometric monitoring of bone healing process around self-drilling orthodontic miniscrews, subjected or not to immediate loading, in rabbit tibiae
Grantee:Gladys Cristina Dominguez Morea
Support Opportunities: Regular Research Grants