Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Development of a carbon nanotube paste electrode modified with zinc phosphate for captopril determination in pharmaceutical and biological samples

Full text
Author(s):
Janegitz, Bruno C. [1, 2] ; Figueiredo-Filho, Luiz C. S. [1] ; Vicentini, Fernando Campanha [1] ; Ribeiro, Maria Fernanda M. [1] ; Suarez, Willian T. [3] ; Fatibello-Filho, Orlando [1] ; Metters, Jonathan P. [4] ; Banks, Craig E. [4]
Total Authors: 8
Affiliation:
[1] Univ Fed Sao Carlos, Dept Quim, Ctr Ciencias Exatas & Tecnol, BR-13560970 Sao Carlos, SP - Brazil
[2] Univ Sao Paulo, Inst Fis Sao Carlos, Grp Nanomed & Nanotoxicidade, BR-13566590 Sao Carlos, SP - Brazil
[3] Univ Fed Vicosa, Dept Quim, BR-36570000 Vicosa, MG - Brazil
[4] Manchester Metropolitan Univ, Div Chem & Environm Sci, Sch Chem & Environm, Fac Sci & Engn, Manchester M1 5GD, Lancs - England
Total Affiliations: 4
Document type: Journal article
Source: ANALYTICAL METHODS; v. 6, n. 5, p. 1324-1329, 2014.
Web of Science Citations: 8
Abstract

We report a novel electrode composite comprising zinc phosphate within a multiwalled carbon nanotube paste electrode matrix which is applied for the detection of trace amounts of captopril (CAP) via square-wave adsorptive anodic stripping voltammetry (SWAdASV); to the best of our knowledge this is the first report on such a composite electrode. Under optimum experimental conditions, the peak current of CAP was found to be linear over the concentration range from 3.7 to 67 mu mol L-1 with a limit of detection of 0.1 mu mol L-1. The proposed method was applied for the successful determination of CAP in commercial tablet excipients and biological samples using the electroanalytical protocol evaluated against the laboratory standard iodometric procedure. Excellent comparability between the two is found suggesting that the former can replace the latter within laboratory settings or can be applied to in-the-field applications. (AU)

FAPESP's process: 10/20754-1 - Development of electrochemical sensors based on nanomaterials for the determination of interest pharmaceutical and environmental species
Grantee:Luiz Carlos Soares de Figueiredo Filho
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/16770-0 - Sensors development based on polymeric films and nanomaterials for several analytical applications
Grantee:Fernando Campanhã Vicentini
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 12/02877-4 - Development of new biosensors using active Nanoesctrutured materials
Grantee:Bruno Campos Janegitz
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 08/09893-0 - Development of biosensors using carbon nanotube and nanoparticles
Grantee:Bruno Campos Janegitz
Support type: Scholarships in Brazil - Doctorate