Efficacy of TiF4 and NaF varnish and solution: a randomized in situ study on enamel erosive-abrasive wear

Author(s)

Levy, Flavia Mauad ^[1] ; Rios, Daniela ^[2] ; Buzalaf, Marilia A. R. ^[1] ; Magalhes, Ana Carolina ^[1]

Affiliation

^[1] Univ Sao Paulo, Dept Biol Sci, BR-17012901 Bauru, SP - Brazil

^[2] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, BR-17012901 Bauru, SP - Brazil

• Document type: Journal article
• Source: CLINICAL ORAL INVESTIGATIONS; v. 18, n. 4, p. 1097-1102, MAY 2014.
• Web of Science Citations: 14

Abstract

This in situ/ex vivo study analysed the anti-erosive/abrasive effect of TiF4 and NaF varnish and solution on enamel wear. Twelve subjects took part in this study which was performed in three periods (phases) with the duration of 5 days each. Each two human enamel specimens per subject were pretreated with experimental NaF varnish or solution (phase A), experimental-TiF4 varnish or solution (phase B) and placebo varnish or untreated control (phase C). The specimens were worn in palatal appliances; one enamel specimen, from each treatment, was subjected to erosion (ERO; cola soft drink, 4 x 90 s/day), and the other specimen was subjected to erosion plus abrasion (ERO + ABR; tooth brushing, 2 x 10 s/day). The tooth wear was quantified by a contact profilometer (micrometre) and analysed using two-way repeated measures ANOVA and Bonferroni's test (n = 12 subjects, p < 0.05). All fluoride varnishes and solutions reduced the enamel wear (around 25 %) significantly compared to the control and placebo varnish. There were no significant differences among the fluoride formulations and between the conditions ERO and ERO + ABR. Therefore, it can be concluded that TiF4 has the same protective potential as NaF formulations to reduce human enamel wear under this experimental in situ model. In vitro studies have indicated a better anti-erosive/abrasive effect of TiF4 compared to NaF varnish. The present in situ study does not support the previous findings. Therefore, any of the tested professional fluoride varnishes in principle could be able to partially reduce enamel wear. (AU)

• FAPESP's process: 08/07105-4 - Evaluation of the effect of an experimental TiF4 varnish compared to NaF varnishes and solutions and to TiF4 solution on erosion and abrasion of enamel and dentin: in vitro and in situ studies
• Grantee: Ana Carolina Magalhães
• Support Opportunities: Regular Research Grants
• FAPESP's process: 08/03727-0 - Evaluation of the effect of an experimental titanium tetrafluoride varnish compared to sodium fluoride varnishes and solutions on erosion and abrasion of enamel and dentin in vitro and in situ
• Grantee: Flavia Mauad Levy Abrahão
• Support Opportunities: Scholarships in Brazil - Post-Doctoral