| Full text | |
| Author(s): |
Modesto, Waleska
[1]
;
Valeria Bahamondes, M.
[1]
;
dos Santos, Priscila Silva
[1]
;
Fernandes, Arlete
[1]
;
Dal'Ava, Natalia
[1]
;
Bahamondes, Luis
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Estadual Campinas, UNICAMP, Natl Inst Hormones & Womens Hlth, Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE; v. 19, n. 4, p. 244-249, AUG 2014. |
| Web of Science Citations: | 5 |
| Abstract | |
Objectives To compare variations in bone mineral density (BMD) and body composition (BC) in depot-medroxyprogesterone acetate (DMPA) users and nonusers after providing counselling on healthy lifestyle habits. Methods An exploratory study in which women aged 18 to 40 years participated: 29 new DMPA users and 25 new non-hormonal contraceptive users. All participants were advised on healthy lifestyle habits: sun exposure, walking and calcium intake. BMD and BC were assessed at baseline and 12 months later. Statistical analysis included the Mann-Whitney test or Student's t-test followed by multiple linear regression analysis. Results Compared to the controls, DMPA users had lower BMD at vertebrae L1 and L4 after 12 months of use. They also had a mean increase of 2 kg in total fat mass and an increase of 2.2% in body fat compared to the non-hormonal contraceptive users. BMD loss at L1 was less pronounced in DMPA users with a calcium intake >= 1 g/day compared to DMPA users with a lower calcium intake. Conclusions DMPA use was apparently associated with lower BMD and an increase in fat mass at 12 months of use. Calcium intake >= 1 g/day attenuates BMD loss in DMPA users. Counselling on healthy lifestyle habits failed to achieve its aims. (AU) | |
| FAPESP's process: | 11/01554-4 - Body composition and bone mineral density in users of depot medroxyprogesterone acetate compared to CIU Tcu380A Intrauterine Device |
| Grantee: | Waleska Oliveira Modesto |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/53293-0 - Prospective study for evaluation of the insulin resistance, lipid metabolism and sub clinical cardiovascular disease in women who initiate the depot-medroxyprogesterone acetate (DMP A) contraceptive method with in follow-up for two years. (Project of scientific research) |
| Grantee: | Luis Guillermo Bahamondes |
| Support Opportunities: | Research Grants - Research in Public Policies for the National Health Care System (PP-SUS) |