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Development of novel magnetic nanocomposites based on hydrogel for evaluation as carrier vehicle of drugs and agricultural inputs

Grant number:18/18697-1
Support Opportunities:Regular Research Grants
Start date: February 01, 2021
End date: July 31, 2023
Field of knowledge:Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
Principal Investigator:Fauze Ahmad Aouada
Grantee:Fauze Ahmad Aouada
Host Institution: Faculdade de Engenharia (FEIS). Universidade Estadual Paulista (UNESP). Campus de Ilha Solteira. Ilha Solteira , SP, Brazil
City of the host institution:Ilha Solteira
Associated researchers:Márcia Regina de Moura Aouada ; Renato Grillo
Associated research grant(s):24/03673-0 - 50th World Polymer Congress - IUPAC MACRO 2024, AR.EXT

Abstract

With the advances of the world technology, the use of conventional methods in agribusiness is decreasing due to the increase of the use of precision agriculture that appears as a modern mechanism, reflecting a new model of productivity together with environment qualification. Linked to precision agriculture, it can be highlighted in the development of biodegradable hydrogels and their nanocomposites as carrier vehicles for controlled release. In parallel, the economy suffers with high cost of inputs used in the medical area. In this way, biomaterials with less cost have been developed. In addition, by the fact of the drugs need of continuous administration, the conventional methods are no most appropriated for application to patients, whereas that these methods have many collateral effects. In this way, the substitution of these methods by controlled release technology opens new perspectives because when the drugs are applied from conventional methods, their release presents a maximum dosage peak losing this effect, reaching an inefficient level. In this sense, the key innovation of this project is to obtain and characterize of hybrid nanocomposites with iron oxide nanoparticles, and to modify nanostructures, such as nanoclay. Aiming their magnetic properties for application in controlled release of agricultural inputs with reuse possibility and in the medical area as carrier vehicle for the drug controlled release with remote activation. The project has as global objective continue the research, partially funded by this agency, related to the synthesis, characterization, and development of nanocomposites based on polysaccharide and inorganic materials as nanoclay and zeolite for agriculture application. (AU)

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Scientific publications (11)
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
ALVES, BRUNO C.; MIRANDA, RENATO DE S.; FRIGIERI, BARBARA M.; ZUCCARI, DEBORA A. P. C.; DE MOURA, MARCIA R.; AOUADA, FAUZE A.; TOKIMATSU, RUIS C.. A 3D Printing Scaffold Using Alginate/Hydroxyapatite for Application in Bone Regeneration. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 26, p. 7-pg., . (13/03643-0, 13/07296-2, 18/18697-1)
WATANUKI FILHO, ADHEMAR; HIGUTI, RICARDO TOKIO; DE MOURA, MARCIA REGINA; AOUADA, FAUZE AHMAD. Synthesis, Application and Effect of Hybrid Nanocomposites Based on Hydrogel and Nanoclay in Cement-Mortars. POLYMERS, v. 14, n. 21, p. 23-pg., . (18/18697-1, 18/13580-9, 13/07296-2)
FERNANDES, RENAN DA SILVA; TANAKA, FABRICIO CERIZZA; FERREIRA JUNIOR, CARLOS ROBERTO; YONEZAWA, UILIAN GABALDI; DE MOURA, MARCIA REGINA; AOUADA, FAUZE AHMAD. PAAm/CMC/nanoclay nanocomposite hydrogel: understanding the influence of initiators on the chain-growth mechanisms. JOURNAL OF POLYMER RESEARCH, v. 29, n. 12, p. 12-pg., . (13/03643-0, 13/07296-2, 18/18697-1)
FILHO, ADHEMAR WATANUKI; DE MOURA, MARCIA REGINA; AOUADA, FAUZE AHMAD. Performance of cementitious mortars containing hydrogel-nanoclay hybrid nanocomposite. Journal of Sol-Gel Science and Technology, v. N/A, p. 18-pg., . (13/07296-2, 18/18697-1, 18/13580-9)
DOS SANTOS, SIDNEY S.; CERQUEIRA, MIGUEL ANGELO; AZEVEDO, ANA GABRIELA; PASTRANA, LORENZO M.; AOUADA, FAUZE AHMAD; TANAKA, FABRICIO C.; PEROTTI, GUSTAVO FRIGI; DE MOURA, MARCIA REGINA. Biotechnological Utilization of Amazonian Fruit: Development of Active Nanocomposites from Bacterial Cellulose and Silver Nanoparticles Based on Astrocaryum aculeatum (Tucumã) Extract. PHARMACEUTICALS, v. 18, n. 6, p. 17-pg., . (13/03643-0, 13/07296-2, 18/18697-1)
TANAKA, FABRICIO C.; YONEZAWA, UILIAN G.; DE MOURA, MARCIA R.; AOUADA, FAUZE A.. Studies of the Sorption-Desorption of Pesticides from Cellulose-Based Derivative Nanocomposite Hydrogels. Molecules, v. 29, n. 20, p. 15-pg., . (13/07296-2, 18/18697-1)
NAVES, HUEBERTON BARBOSA; STAFUSSA, ANA PAULA; MADRONA, GRASIELE SCARAMAL; TANAKA, FABRICIO CERIZZA; AOUADA, FAUZE AHMAD; DE MOURA, MARCIA REGINA. Development of New Edible Biodegradable Films Containing Camu-Camu and Agro-Industry Residue. POLYMERS, v. 16, n. 13, p. 12-pg., . (13/07296-2, 18/18697-1, 13/03643-0)
M. A. F. CALESCO; A. WATANUKI FILHO; M. R. DE MOURA; F. A. AOUADA. . Cerâmica, v. 68, n. 385, p. 97-107, . (13/03643-0, 13/07296-2, 18/18697-1, 18/13580-9)
DE LIMA, PEDRO HENRIQUE CORREIA; TAVARES, ALBANIZA ALVES; SILVA, SUEDINA MARIA DE LIMA; DE MOURA, MARCIA REGINA; AOUADA, FAUZE AHMAD; GRILLO, RENATO. Recent advances on nanohybrid systems constituting clay-chitosan with organic molecules-A review. APPLIED CLAY SCIENCE, v. 226, p. 14-pg., . (19/06170-1, 18/18697-1)
WATANUKI FILHO, ADHEMAR; YONEZAWA, UILIAN GABALDI; DE MOURA, MARCIA REGINA; AOUADA, FAUZE AHMAD. Physicochemical Properties of Hybrid Biodegradable Silica-Hydrogel Composites. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 26, p. 9-pg., . (13/03643-0, 13/07296-2, 18/18697-1)
RABELO, LACAN S.; TANAKA, FABRICIO C.; DOS SANTOS, SIDNEY S.; AOUADA, FAUZE A.; DE MOURA, MARCIA R.. The Future of Sustainable Packaging: Exploring Biodegradable Solutions Through Extrusion, Thermo-Expansion, 3D Printing and Supercritical Fluid from Agro-Industry Waste. FOODS, v. 14, n. 23, p. 21-pg., . (18/18697-1, 13/03643-0, 13/07296-2)