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Stabilization and encapsulation of natural colorants and application in the development of packaging and cosmetics

Abstract

Consumers are increasingly concerned about their health and the composition of their food and personal care products. For this reason, the pharmaceutical and food industries have replaced synthetic colorants with natural ones, which, in addition to pleasing the public, can confer advantages to materials and foods, attributing them antioxidant and antimicrobial action. In this context, this project aims to develop functional creams and packaging with natural colorants that have functional advantages over similar ones on the market, are safe, have sustainable production and composition with natural ingredients. Additionally, they must be economically viable and with the possibility of insertion in the Brazilian market. To do so, first, we will evaluate the stability of different natural colorants of azafilones and carotenoids to select the best compound for application. For creams, we will check the stability of colorants in mixtures of fatty acids and surfactants to select compatible components for this purpose. Then, we will define emulsion compositions for the production of colorant creams, which will have their stability, safety and antioxidant action evaluated. For packaging (biodegradable films), we will first encapsulate the colorants in maltodextrin and chitosan and then develop biodegradable films with chitosan for use as food packaging. The formed biodegradable films will be evaluated for their strength, durability, antioxidant and antimicrobial properties, food preservation potential and organoleptic changes in butter and meat. After developing two satisfactory products, we will also carry out a technical-economic evaluation and market research to assess their economic viability and market insertion potential. Therefore, the project foresees the complete development of two products using natural colorants. (AU)

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Scientific publications (8)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FREITAS, AMANDA NOLI; REMONATTO, DANIELA; MIOTTI JR, RODNEY HELDER; DO NASCIMENTO, JOAO FRANCISCO CABRAL; MOURA, ADRIANA CANDIDO DA SILVA; EBINUMA, VALERIA DE CARVALHO SANTOS; DE PAULA, ARIELA VELOSO. Adsorption of extracellular lipase in a packed-bed reactor: an alternative immobilization approach. Bioprocess and Biosystems Engineering, v. 47, n. 10, p. 15-pg., . (21/13147-6, 23/01368-3, 21/06686-8, 20/09592-1)
DE LIMA, ISABELLE ALMEIDA; LIMA, CAIO DE AZEVEDO; DE ANNUNZIO, SARAH RAQUEL; DE OLIVEIRA, FERNANDA; DA SILVA, SILVIO SILVERIO; FONTANA, CARLA RAQUEL; SANTOS-EBINUMA, VALERIA DE CARVALHO. Fungal derived dye as potential photosensitizer for antimicrobial photodynamic therapy. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 264, p. 9-pg., . (21/06686-8, 23/01368-3, 18/09088-1, 22/14603-8, 18/23015-7, 21/09175-4, 19/04294-5)
MUSSAGY, CASSAMO U.; DIAS, ANA C. R. V.; SANTOS-EBINUMA, VALERIA C.; SADEK, M. SHAABAN; AHMAD, MUSHTAQ; DE ANDRADE, CLEVERTON R.; HADDAD, FELIPE F.; DOS SANTOS, JEAN L.; SCARIM, CAUE B.; PEREIRA, JORGE F. B.; et al. Is the carotenoid production from Phaffia rhodozyma yeast genuinely sustainable? a comprehensive analysis of biocompatibility, environmental assessment, and techno-economic constraints. Bioresource Technology, v. 397, p. 12-pg., . (21/06686-8, 23/01368-3)
MAGALHAES, FLAVIA F.; NEVES, MARCIA C.; PEDRO, AUGUSTO Q.; FREIRE, MARA G.; SANTOS-EBINUMA, VALERIA C.; TAVARES, ANA P. M.. Recombinant laccase biosynthesis for efficient polydopamine coating. Biochemical Engineering Journal, v. 212, p. 11-pg., . (21/06686-8, 23/01368-3)
VERISSIMO, NATHALIA VIEIRA PORPHIRIO; MUSSAGY, CASSAMO USEMANE; BENTO, HEITOR BUZETTI SIMOES; PEREIRA, JORGE FERNANDO BRANDAO; SANTOS-EBINUMA, VALERIA DE CARVALHO. Ionic liquids and deep eutectic solvents for the stabilization of biopharmaceuticals: A review. BIOTECHNOLOGY ADVANCES, v. 71, p. 22-pg., . (21/06686-8, 23/01368-3, 18/06908-8, 23/10479-3)
SEGATO, TALITA CRISTINA MENA; CAETANO, ERIKA LEAO AJALA; MOTT, RAFAELLA DE BARROS; IBANEZ, NATASHA LIEN DE ALMEIDA; FRATTES, CAMILA DA CUNHA; LIMA, CAIO DE AZEVEDO; ALVES, MONICA RODRIGUES; SANTOS-EBINUMA, VALERIA CARVALHO; GROTTO, DENISE. A 90-day oral toxicity study evaluation of azaphilone derived from Talaromyces amestolkiae: A natural food colorant. Food and Chemical Toxicology, v. 200, p. 10-pg., . (23/01368-3, 22/02015-4, 21/06686-8)
GALVAN, KARINA LIZZETH PEDRAZA; VERISSISMO, NATHALIA VIEIRA PORHIRIO; SANTANA, JAMILLE SANTOS; LEMOS, PAULO VITOR FRANCA; DE SOUZA, CAROLINA OLIVEIRA; CARDOSO, LUCAS GUIMARAES; ASSIS, DENILSON DE JESUS; MARCELINO, HENRIQUE RODRIGUES; DE OLIVEIRA, THAMILA THALLINE BATISTA; BIASOTO, ALINE TELLES CAMARA; et al. Encapsulation of polyketide colorants in chitosan and maltodextrin microparticles. International Journal of Biological Macromolecules, v. 269, p. 13-pg., . (21/06686-8, 23/01368-3, 23/10479-3)
DE OLIVEIRA, F.; DIAS, A. C.; SANCHEZ-MUNOZ, S.; BALBINO, T. R.; SANTOS-EBINUMA, V. C.; DA SILVA, S. S.. Sustainability feasibility of fungi-based biocolorants by biotechnological routes. CHEMICAL ENGINEERING JOURNAL, v. 494, p. 18-pg., . (21/06686-8, 23/01368-3, 21/09175-4, 22/14603-8)