| Grant number: | 10/50193-1 |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |
| Start date: | August 01, 2010 |
| End date: | July 31, 2016 |
| Field of knowledge: | Physical Sciences and Mathematics - Oceanography - Biological Oceanography |
| Principal Investigator: | Pio Colepicolo Neto |
| Grantee: | Pio Colepicolo Neto |
| Host Institution: | Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| City of the host institution: | São Paulo |
| Associated scholarship(s): | 12/12235-0 - Identification of metal stress response transcripts in Gracilaria domingensis,
BP.DR 12/00933-4 - Biochemical biomarkers in macroalgae of the genus Gracilaria exposed to metals, BP.DR 11/16072-5 - Use of genetic and biochemical engineering in Chlamydomonas reinhardtii aiming the increase of the lipid level for biofuel production, BP.MS + associated scholarships - associated scholarships |
Abstract
In order to survive in a highly competitive environment, marine algae have to develop defense strategies that result in a tremendous diversity of compounds from different metabolic pathways. Recent trends in drug research from natural sources have shown that algae are promising organisms to furnish novel biochemically active compounds. The aim of this project is to study the compounds biosynthesized by algae with potential economic impact in food science, pharmaceutical industry and public health. Emphasis is given to antioxidants, bactericide, antifungal and UV absorber molecules. Macroalgae will be collected at Sao Paulo State marine coastal and assays will be performed at the lab. Extracts with potential activities will be purifies and the chemical structure will be elucidated. (AU)
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