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Comparative study between LED and laser as phototherapies against chemotherapy-induced oral mucositis

Grant number: 10/03662-6
Support Opportunities:Regular Research Grants
Duration: October 01, 2010 - September 30, 2011
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Alyne Simões Gonçalves
Grantee:Alyne Simões Gonçalves
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated researchers:Carlos de Paula Eduardo ; Luana de Campos


Patients submitted to chemotherapy and/or head and neck radiotherapy are usually affected by oral complications, especially oral mucositis and severe pain, which demands support therapy. Although the management of such oral complications by phototherapy with laser (LPT) and with LEDs has been studied, the comparison between these therapies has not been studied yet. Thus, the aim of this study is to compare the effect of these two therapies against chemotherapy-induced oral mucositis (CIOM) and pain. Forty patients with CIOM will be submitted to phototherapy according to 2 groups: G1, red low power laser; G2, red LED. The treatment will be done during 10 days using an InGaAlP laser (660nm/40mW/6Jcm-²/0.24J per point) or LED phototherapy, 0.24J per point/80mW/630nm. CIOM grade will be assessed at each session in accordance to the World Health Organization (WHO) and patient pain will be measured by means of the visual analogue scale (VAS). (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CARNEIRO FREITAS, ANA CAROLINA; CAMPOS, LUANA; BRANDAO, THAIS BIANCA; CRISTOFARO, MARCIO; EDUARDO, FERNANDA DE PAULA; LUIZ, ANA CLAUDIA; MARQUES, MARCIA MARTINS; EDUARDO, CARLOS DE PAULA; SIMOES, ALYNE. Chemotherapy-Induced Oral Mucositis: Effect of LED and Laser Phototherapy Treatment Protocols. Photomedicine and Laser Surgery, v. 32, n. 2, p. 81-87, . (11/14013-1, 10/03662-6)

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