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Effects of concurrent training on inflammatory and morphofunctional responses in obese middle-aged men

Grant number: 11/09446-6
Support type:Regular Research Grants
Duration: October 01, 2011 - March 31, 2014
Field of knowledge:Health Sciences - Physical Education
Principal researcher:Claudia Regina Cavaglieri
Grantee:Claudia Regina Cavaglieri
Home Institution: Faculdade de Educação Física (FEF). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Assoc. researchers:Jose Rocha ; Mara Patricia Traina Chacon Mikahil ; Maria Luisa Bellotto Bortoleto

Abstract

The aim of this study is to compare the concurrent training (CT) responses on the biochemical and morphofunctional markers in obese middle-aged men. Forty obese men [body mass index (BMI) =30-34.9 kg/m²] distributed in the obese control group (OCG; n=20) and obese group CT (OCT; n=20) will be recruited. Body composition, cardiorespiratory fitness and muscular strength of individuals will be performed by anthropometric assessment, cardiopulmonary test and one maximum repetition test (1RM), respectively. Blood samples will be collected before the beginning of the study (M1), as well as after 8 (M2), 16 (M3) and 24 weeks (M4), and for each moment resistin, adiponectin, leptin, interleukin (IL) 6 (IL-6), IL-10, IL-15, prostaglandin (PGE2), tumor necrosis factor alpha (TNF-±), C-reactive protein (CRP), cortisol, testosterone, lactate dehydrogenase (LDH), creatine kinase (CK) and complete blood count will be analyzed. The CT program will be composed of both strength (6 exercises/3X10 repetitions/1 minute rest between sets) and endurance (30 minutes walking or running at 50-85% of VO2max) training performed in the same session, three times per week and divided into three phases (E1, E2 and E3), each with eight weeks duration and different intensities. It is expected that the CT protocol can decrease the body fat and the inflammatory biomarkers. (AU)

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Scientific publications (5)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BELLOTTO, M. L.; CASTRO, A.; BONFANTE, I. L. P.; BRUNELLI, D. T.; CHACON-MIKAHIL, M. P. T.; CAVAGLIERI, C. R. Association of food quality index with subclinical inflammation in middle-aged obese men. MEDITERRANEAN JOURNAL OF NUTRITION AND METABOLISM, v. 14, n. 2, p. 163-171, 2021. Web of Science Citations: 0.
PADILHA BONFANTE, IVAN LUIZ; TRAINA CHACON-MIKAHIL, MARA PATRICIA; BRUNELLI, DIEGO TREVISAN; GASPARI, ARTHUR FERNANDES; DUFT, RENATA GARBELLINI; OLIVEIRA, ALEXANDRE GABARRA; ARAUJO, TIAGO GOMES; ABDALLA SAAD, MARIO JOSE; CAVAGLIERI, CLAUDIA REGINA. Obese with higher FNDC5/Irisin levels have a better metabolic profile, lower lipopolysaccharide levels and type 2 diabetes risk. ARCHIVES OF ENDOCRINOLOGY METABOLISM, v. 61, n. 6, p. 524-533, DEC 2017. Web of Science Citations: 6.
PADILHA BONFANTE, IVAN LUIZ; TRAINA CHACON-MIKAHIL, MARA PATRICIA; BRUNELLI, DIEGO TREVISAN; GASPARI, ARTHUR FERNANDES; DUFT, RENATA GARBELLINI; LOPES, WENDELL ARHUR; BONGANHA, VALERIA; LIBARDI, CLEITON AUGUSTO; CAVAGLIERI, CLAUDIA REGINA. Combined training, FNDC5/irisin levels and metabolic markers in obese men: A randomised controlled trial. European Journal of Sport Science, v. 17, n. 5, p. 629-637, JUN 2017. Web of Science Citations: 9.
IVAN LUIZ PADILHA BONFANTE; MARA PATRICIA TRAINA CHACON-MIKAHIL; DIEGO TREVISAN BRUNELLI; ARTHUR FERNANDES GÁSPARI; RENATA GARBELLINI DUFT; ALEXANDRE GABARRA OLIVEIRA; TIAGO GOMES ARAUJO; MARIO JOSE ABDALLA SAAD; CLÁUDIA REGINA CAVAGLIERI. Obese with higher FNDC5/Irisin levels have a better metabolic profile, lower lipopolysaccharide levels and type 2 diabetes risk. ARCHIVES OF ENDOCRINOLOGY METABOLISM, v. 61, n. 6, p. -, Dez. 2017.
BRUNELLI, DIEGO T.; CHACON-MIKAHIL, MARA PATRICIA T.; GASPARI, ARTHUR F.; LOPES, WENDELL ARTHUR; BONGANHA, VALERIA; BONFANTE, IVAN LUIZ P.; BELLOTTO, MARIA LUISA; LIBARDI, CLEITON AUGUSTO; CAVAGLIERI, CLAUDIA REGINA. Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 47, n. 10, p. 2207-2215, OCT 2015. Web of Science Citations: 13.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.