Molecular typing of Acinetobacter baumannii carbapenem resistent isolated in a University Hospital

• Grant number: 12/08210-1
• Support Opportunities: Regular Research Grants
• Duration: September 01, 2012 - August 31, 2013
• Field of knowledge: Biological Sciences - Microbiology - Applied Microbiology
• Principal Investigator: Ana Lúcia da Costa Darini
• Grantee: Ana Lúcia da Costa Darini
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated researchers: Eduardo Carneiro Clímaco

Abstract

Acinetobacter baumannii is an important pathogen in hospital infections and recently is being involved in clinical reports of carbapenem resistance. The aim of this project is to investigate clones of A. baumannii carbapenem resistant (CRAB) isolated from April to November 2008, from patients of the Hospital Universitário da Universidade Federal de Juiz de Fora, MG, Brazil and to determine the genes responsible for the carbapenem resistance. After PFGE, MLST (Multilocus Sequence Typing) will be performed in order to compare with other in specific data base. The results will contribute to knowledge of CRAB in the hospital involved and relationship with other A. baumannii strains. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CLIMACO, EDUARDO CARNEIRO; DE OLIVEIRA, MILENA LOCCI; PITONDO-SILVA, ANDRE; OLIVEIRA, MURILO GOMES; MEDEIROS, MICHELI; LINCOPAN, NILTON; DA COSTA DARINI, ANA LUCIA. Clonal complexes 104, 109 and 113 playing a major role in the dissemination of OXA-carbapenemase-producing Acinetobacter baumannii in Southeast Brazil. INFECTION GENETICS AND EVOLUTION, v. 19, p. 127-133, OCT 2013. (12/08210-1)