Heart rate recovery after exercise: regulatory mechanisms

• Grant number: 13/04997-0
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2013
• End date: July 31, 2015
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Cláudia Lúcia de Moraes Forjaz
• Grantee: Cláudia Lúcia de Moraes Forjaz
• Host Institution: Escola de Educação Física e Esporte (EEFE). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Decio Mion Junior ; Taís Tinucci

Abstract

Post-exercise heart rate recovery (HRR) provides the assessment of the cardiac autonomic responsiveness to a physiological stress. Studies have shown that reduced HRR values are associated with greater mortality rates. Hypertension is a high-prevalent disease with poor cardiovascular prognostic. Studies have shown a reduced HRR in hypertensive subjects compared with normotensives. This autonomic dysfunction may reflect a lower efficiency of the cardiovascular control mechanisms, such as central command, mechanoreflex, metaboreflex and thermoregulation. Nevertheless, the role and the impairment of these mechanisms on the HRR reduction in this population are not clear. The aim of this study, therefore, is to investigate the role of the cardiovascular control mechanisms on HRR of hypertensive. 25 hypertensive and 25 normotensive subjects will undergo 5 experimental sessions conducted in a random order. During the sessions, measurements will be done at rest, exercise (cycle ergometer, 30 min, 70% of maximal workload) and recovery. In each sessions, the post-exercise recovery will be conducted in different ways: a) passive recovery - absence of movement; b) active recovery - maintaining the movement at a lower intensity; c) assisted recovery - maintaining of the movement at a lower intensity by an external force; d) passive recovery with circulatory occlusion and e) passive recovery with cooling ventilation. In all the sessions, the electrocardiogram, respiratory signal and photoplethysmographic blood pressure will be continuously recorded. Moreover, blood lactate concentration will be measured in specific moments. Each two sessions results will be compared for assessing the role of the cardiovascular control mechanism on HRR: central command (b vs. c), mechanoreflex (a vs. c), metaboreflex (a vs. d) and thermoregulation (a vc. e.). Data will be analyzed by a 2-way ANOVA for repeated measures, using group and the session as the main within factors. (AU)

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PECANHA, TIAGO; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; DA SILVA JUNIOR, NATAN DANIEL; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION-JUNIOR, DECIO; DE MORAES FORJAZ, CLAUDIA LUCIA. Metaboreflex activation delays heart rate recovery after aerobic exercise in never-treated hypertensive men. JOURNAL OF PHYSIOLOGY-LONDON, v. 594, n. 21, p. 6211-6223, NOV 2016. (13/05519-4, 13/04997-0)

BRITO, LEANDRO; PECANHA, TIAGO; TINUCCI, TAIS; SILVA-JUNIOR, NATAN; COSTA, LUIZ; FORJAZ, CLAUDIA. Time of day affects heart rate recovery and variability after maximal exercise in pre-hypertensive men. CHRONOBIOLOGY INTERNATIONAL, v. 32, n. 10, p. 1385-1390, 2015. (13/05519-4, 11/03584-8, 13/04997-0)

PECANHA, TIAGO; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; SILVA, NATAN DANIEL; COUTO, PATRICIA GUIMARAES; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION, DECIO; LOW, DAVID A.; et al. Activation of Mechanoreflex, but not Central Command, Delays Heart Rate Recovery after Exercise in Healthy Men. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v. 42, n. 07, p. 602-609, JUN 2021. (13/04997-0, 13/05519-4)

PECANHA, TIAGO; FORJAZ, CLAUDIA; LOW, DAVID. Passive Heating Impairs Cardiac Autonomic Regulation during Exercise and Post-Exercise Recovery. FASEB JOURNAL, v. 31, p. 1-pg., 2017-04-01. (13/04997-0, 13/05519-4, 15/15466-0)

PECANHA, TIAGO; LOW, DAVID; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; DA SILVA-JUNIOR, NATAN DANIEL; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION-JUNIOR, DECIO; FORJAZ, CLAUDIA LUCIA DE MORAES. Effects of postexercise cooling on heart rate recovery in normotensive and hypertensive men. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, v. 40, n. 2, DEC 2019. (15/15466-0, 13/04997-0, 13/05519-4)