Botanical repellents and nanotechnology: development of systems for pest control in agriculture

• Grant number: 15/15617-9
• Support Opportunities: Regular Research Grants
• Start date: December 01, 2015
• End date: November 30, 2017
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Principal Investigator: Leonardo Fernandes Fraceto
• Grantee: Leonardo Fernandes Fraceto
• Host Institution: Instituto de Ciência e Tecnologia. Universidade Estadual Paulista (UNESP). Campus de Sorocaba. Sorocaba , SP, Brazil
• Associated researchers: Halley Caixeta de Oliveira ; Renata de Lima
• Associated research grant(s): 16/50196-7 - Design and development of nanoparticles aiming agriculture and enviromental applications: a bilateral cooperation between UNESP/Sorocaba and HWU, AP.R SPRINT; 16/50003-4 - Evaluation of the respiratory bioreactivity of nanopesticides and development of safe, effective pesticides, AP.R SPRINT

Abstract

The pests and insects, have been a major cause of crop losses worldwide. In Brazil alone these losses may reach 7.7 % per year. The whitefly (Bemisia tabaci) is one of the main pests present in Brazil, being found in many regions. The major concern with this type of pest, is the vast diversity of hosts, leading to losses of 100 % due to pathogens transmission capacity. The use of synthetic insecticides has been the main way to control this kind of pest, however, the adverse effects of these compounds both for the environment and to human health has motivated the search for lower impact alternatives. In this context, various mechanisms have been studied to minimize this damage, such as the development of modified release systems using biodegradable polymers and proteins. Added to this, the action of botanical insecticides and repellents have also demonstrated potential to combat these pests, due to lower impacts of these natural products. Therefore, the present project aims to develop (preparation and characterization) of nanocarriers systems produced from polymers chitosan and zein protein to repellents Botanical (linalool, geraniol and citronellal), as well as the potential effects quote and phytotoxic of these systems. The project also seeks to incorporate these systems into matrices of crosslinked gels in order to produce release of these active devices in the field. In addition they will be made repellent activity tests of these systems and devices against whitefly (Bemisia tabaci) in different cultures: Tomato (Solanum lycopersicum), beans (Phaseolus vulgaris) and soybean (Glycine max). The importance of this project lies in the dimension of the agricultural sector represents for the Brazilian and world economies. Also the crop protection market is growing annually, with Brazil being one of the leaders in the consumption of these products. Thus, the development of technology with high added value to the pest control area in agriculture is promising as more efficient systems can be produced in pest control, less impacting the environment and consequently to human health (AU)

Scientific publications

(18)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CAMPOS, ESTEFNIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.. Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential Biotechnological Applications. FRONTIERS IN CHEMISTRY, v. 5, NOV 7 2017. (14/20273-4, 15/15617-9, 14/20286-9)

PASCOLI, MONICA; DE LIMA, RENATA; FRACETO, LEONARDO F.. Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review. FRONTIERS IN CHEMISTRY, v. 6, JAN 25 2018. (15/17120-4, 15/15617-9)

DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; FRACETO, LEONARDO FERNANDES. Recent Developments and Challenges for Nanoscale Formulation of Botanical Pesticides for Use in Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 34, p. 8898-8913, AUG 29 2018. (15/15617-9, 14/20286-9)

FRACETO, LEONARDO F.; MARUYAMA, CINTIA R.; GUILGER, MARIANA; MISHRA, SANDHYA; KESWANI, CHETAN; SINGH, HARIKESH BAHADUR; DE LIMA, RENATA. Trichoderma harzianum-based novel formulations: potential applications for management of Next-Gen agricultural challenges. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, v. 93, n. 8, p. 2056-2063, AUG 2018. (16/13692-6, 15/15617-9, 15/18231-4)

MISHRA, SANDHYA; KESWANI, CHETAN; ABHILASH, P. C.; FRACETO, LEONARDO F.; SINGH, HARIKESH BAHADUR. Integrated Approach of Agri-nanotechnology: Challenges and Future Trends. FRONTIERS IN PLANT SCIENCE, v. 8, APR 4 2017. (15/15617-9)

JACQUES, MAURICIO T.; OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; FRACETO, LEONARDO F.; AVILA, DAIANA SILVA. Safety assessment of nanopesticides using the roundworm Caenorhabditis elegans. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, v. 139, p. 245-253, MAY 2017. (14/20273-4, 15/15617-9, 14/20286-9)

DE OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; PEREIRA, ANDERSON E. S.; PASQUOTO, TATIANE; LIMA, RENATA; GRILLO, RENATO; DE ANDRADE, DANIEL JUNIOR; DOS SANTOS, FABIANO APARECIDO; FRACETO, LEONARDO FERNANDES. Zein Nanoparticles as Eco-Friendly Carrier Systems for Botanical Repellents Aiming Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 6, p. 1330-1340, FEB 14 2018. (15/15617-9, 14/20286-9)

SIBAJA LUIS, ANGELICA IRASEMA; RAMOS CAMPOS, ESTEFANIA VANGELIE; DE OLIVEIRA, JHONES LUIZ; FRACETO, LEONARDO FERNANDES. Trends in aquaculture sciences: from now to use of nanotechnology for disease control. Reviews in Aquaculture, v. 11, n. 1, p. 119-132, FEB 2019. (14/20273-4, 15/15617-9, 14/20286-9)

DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; PEREIRA, ANDERSON E. S.; NUNES, LUCAS E. S.; DA SILVA, CAMILA C. L.; PASQUOTO, TATIANE; LIMA, RENATA; SMANIOTTO, GIOVANI; POLANCZYK, RICARDO ANTONIO; FRACETO, LEONARDO F.. Geraniol Encapsulated in Chitosan/Gum Arabic Nanoparticles: A Promising System for Pest Management in Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 21, p. 5325-5334, MAY 30 2018. (15/15617-9, 14/20286-9)

DIEGO FARIA COLA; TATIANE PASQUOTO; MARIANA GUILGER; RENATA DE LIMA; CAMILA MORAIS GONÇALVES DA SILVA; LEONARDO FERNANDES FRACETO. SISTEMAS CARREADORES LIPÍDICOS NANOESTRUTURADOS PARA IVERMECTINA E METOPRENO VISANDO CONTROLE DE PARASITAS. Química Nova, v. 39, n. 9, p. 1034-1043, 2016-11-00. (15/15617-9, 13/24788-6, 13/12322-2)

CAMPOS, ESTEFANIA V. R.; DE OLIVEIRA, JHONES L.; PASCOLI, MONICA; DE LIMA, RENATE; FRACETO, LEONARDO F.. Neem Oil and Crop Protection: From Now to the Future. FRONTIERS IN PLANT SCIENCE, v. 7, OCT 13 2016. (14/20286-9, 13/12322-2, 15/17120-4, 14/20273-4, 15/15617-9)

NAKASATO, DANIELE Y.; PEREIRA, ANDERSON E. S.; OLIVEIRA, JHONES L.; OLIVEIRA, HALLEY C.; FRACETO, LEONARDO F.. Evaluation of the effects of polymeric chitosan/tripolyphosphate and solid lipid nanoparticles on germination of Zea mays, Brassica rapa and Pisum sativum. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, v. 142, p. 369-374, AUG 2017. (13/12322-2, 15/15617-9)

PASCOLI, MONICA; DE LIMA, RENATA; FRACETO, LEONARDO F.. Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review. RONTIERS IN CHEMISTR, v. 6, p. 5-pg., 2018-01-25. (15/17120-4, 15/15617-9)

CAMPOS, ESTEFANIA V. R.; PROENCA, PATRICIA L. F.; OLIVEIRA, JHONES L.; BAKSHI, MANSI; ABHILASH, P. C.; FRACETO, LEONARDO F.. Use of botanical insecticides for sustainable agriculture: Future perspectives. ECOLOGICAL INDICATORS, v. 105, p. 483-495, OCT 2019. (14/20273-4, 15/15617-9, 14/20286-9)

SOUSA, GUSTAVO F. M.; GOMES, DIEGO G.; CAMPOS, ESTEFANIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.; STOLL-MOREIRA, RENATE; OLIVEIRA, HALLEY C.. Post-Emergence Herbicidal Activity of Nanoatrazine Against Susceptible Weeds. FRONTIERS IN ENVIRONMENTAL SCIENCE, v. 6, MAR 14 2018. (15/15617-9, 14/20286-9)

CAMPOS, ESTEFANIA V. R.; OLIVEIRA, JHONES L.; ZAVALA-BETANCOURT, SARA A.; LEDEZMA, ANTONIO S.; ARIAS, EDUARDO; MOGGIO, IVANA; ROMERO, JORGE; FRACETO, LEONARDO F.. Development of stained polymeric nanocapsules loaded with model drugs: Use of a fluorescent poly(phenyleneethynylene). COLLOIDS AND SURFACES B-BIOINTERFACES, v. 147, p. 442-449, NOV 1 2016. (14/20286-9, 15/15617-9, 14/20273-4)

PEREIRA, A. E. S.; SANDOVAL-HERRERA, I. E.; ZAVALA-BETANCOURT, S. A.; OLIVEIRA, H. C.; LEDEZMA-PEREZ, A. S.; ROMERO, J.; FRACETO, L. F.. gamma-Polyglutamic acid/chitosan nanoparticles for the plant growth regulator gibberellic acid: Characterization and evaluation of biological activity. Carbohydrate Polymers, v. 157, p. 1862-1873, FEB 10 2017. (15/15617-9, 13/12322-2)

CAMPOS, ESTEFNIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.. Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential Biotechnological Applications. RONTIERS IN CHEMISTR, v. 5, p. 15-pg., 2017-11-07. (14/20286-9, 15/15617-9, 14/20273-4)

Filed patent(s) as a result of this research project