Development of modified release systems based on zein and chitosan for botanical repellents aiming the control of whitefly (Bemisia tabaci) in different cultures

• Grant number: 14/20286-9
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): March 01, 2015
• Effective date (End): August 31, 2018
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Principal Investigator: Leonardo Fernandes Fraceto
• Grantee: Jhones Luiz de Oliveira
• Host Institution: Instituto de Ciência e Tecnologia. Universidade Estadual Paulista (UNESP). Campus de Sorocaba. Sorocaba , SP, Brazil

Abstract

Pests and insects, have been a major cause of crop losses worldwide. Only in Brazil these losses may reach 7.7% per year. Whitefly (Bemisia tabaci) is a major pest present in Brazil, being found in many regions. The major concern with this type of pest, is the vast diversity of hosts, which may lead to losses of 100% capacity due to transmission of plant pathogens. The use of synthetic insecticides has been the main way to control this type of pest, however, the adverse effects of these compounds to both the environment and for human health effects has motivated the search for a less impactant alternative. In this context, various mechanisms have been studied to minimize this damage, such as the development of modified release systems using biodegradable polymers and proteins. Allied to this, the use of botanical insecticides and repellents has also demonstrated potential to combat these pests, due to lower impacts of these natural products. Therefore, this project aims at developing (preparation and characterization) of nanocarriers systems produced from polymers chitosan and zein protein for botanical repellents (geraniol and citronellal), as well as the effects phytotoxic and citotoxic these systems. The project also aims to incorporate these systems into arrays of cross-linked gels, in order to produce devices for release of these compounds in the field. In addition, will be performed tests of repellent activity of these systems and devices against whitefly (Bemisia tabaci) in different cultures:Tomato (Solanum lycopersicum), beans (Phaseolus vulgaris) and soybean (Glycine max). The importance of this project lies in the dimension of agricultural sector for the Brazilian and world economy, allied to this the market agrochemicals is growing annually, with Brazil being one of the leaders in the consumption of these products. Therefore, the development of high technology to the area of pest control in agriculture is promising since it can be made more efficient systems to control pests, less impacting to the environment and consequently to human health.

Scientific publications

(13)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CAMPOS, ESTEFNIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.. Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential Biotechnological Applications. FRONTIERS IN CHEMISTRY, v. 5, NOV 7 2017. (14/20273-4, 15/15617-9, 14/20286-9)

DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; PEREIRA, ANDERSON E. S.; NUNES, LUCAS E. S.; DA SILVA, CAMILA C. L.; PASQUOTO, TATIANE; LIMA, RENATA; SMANIOTTO, GIOVANI; POLANCZYK, RICARDO ANTONIO; FRACETO, LEONARDO F.. Geraniol Encapsulated in Chitosan/Gum Arabic Nanoparticles: A Promising System for Pest Management in Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 21, p. 5325-5334, MAY 30 2018. (15/15617-9, 14/20286-9)

CAMPOS, ESTEFANIA V. R.; DE OLIVEIRA, JHONES L.; PASCOLI, MONICA; DE LIMA, RENATE; FRACETO, LEONARDO F.. Neem Oil and Crop Protection: From Now to the Future. FRONTIERS IN PLANT SCIENCE, v. 7, OCT 13 2016. (14/20286-9, 13/12322-2, 15/17120-4, 14/20273-4, 15/15617-9)

DE OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; PEREIRA, ANDERSON E. S.; PASQUOTO, TATIANE; LIMA, RENATA; GRILLO, RENATO; DE ANDRADE, DANIEL JUNIOR; DOS SANTOS, FABIANO APARECIDO; FRACETO, LEONARDO FERNANDES. Zein Nanoparticles as Eco-Friendly Carrier Systems for Botanical Repellents Aiming Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 6, p. 1330-1340, FEB 14 2018. (15/15617-9, 14/20286-9)

SIBAJA LUIS, ANGELICA IRASEMA; RAMOS CAMPOS, ESTEFANIA VANGELIE; DE OLIVEIRA, JHONES LUIZ; FRACETO, LEONARDO FERNANDES. Trends in aquaculture sciences: from now to use of nanotechnology for disease control. Reviews in Aquaculture, v. 11, n. 1, p. 119-132, FEB 2019. (14/20273-4, 15/15617-9, 14/20286-9)

DE OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; CAMARA, MARCELA CANDIDO; DELLA VECHIA, JAQUELINE FRANCIOSI; SOARES DE MATOS, SIDNEIA TEREZINHA; DE ANDRADE, DANIEL JUNIOR; GONCALVES, KELLY CRISTINA; DO NASCIMENTO, JOACIR; POLANCZYK, RICARDO ANTONIO; DE ARAUJO, DANIELE RIBEIRO; et al. Hydrogels Containing Botanical Repellents Encapsulated in Zein Nanoparticles for Crop Protection. ACS APPLIED NANO MATERIALS, v. 3, n. 1, p. 207-217, JAN 2020. (14/20286-9, 17/21004-5)

DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; FRACETO, LEONARDO FERNANDES. Recent Developments and Challenges for Nanoscale Formulation of Botanical Pesticides for Use in Sustainable Agriculture. Journal of Agricultural and Food Chemistry, v. 66, n. 34, p. 8898-8913, AUG 29 2018. (15/15617-9, 14/20286-9)

DE OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; GERMANO-COSTA, TAIS; LIMA, RENATA; DELLA VECHIA, JAQUELINE FRANCIOSI; SOARES, SIDNEIA TEREZINHA; DE ANDRADE, DANIEL JUNIOR; GONCALVES, KELLY CRISTINA; DO NASCIMENTO, JOACIR; POLANCZYK, RICARDO ANTONIO; et al. Association of zein nanoparticles with botanical compounds for effective pest control systems. Pest Management Science, v. 75, n. 7, p. 1855-1865, JUL 2019. (17/21004-5, 14/20286-9)

JACQUES, MAURICIO T.; OLIVEIRA, JHONES L.; CAMPOS, ESTEFANIA V. R.; FRACETO, LEONARDO F.; AVILA, DAIANA SILVA. Safety assessment of nanopesticides using the roundworm Caenorhabditis elegans. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, v. 139, p. 245-253, MAY 2017. (14/20273-4, 15/15617-9, 14/20286-9)

SOUSA, GUSTAVO F. M.; GOMES, DIEGO G.; CAMPOS, ESTEFANIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.; STOLL-MOREIRA, RENATE; OLIVEIRA, HALLEY C.. Post-Emergence Herbicidal Activity of Nanoatrazine Against Susceptible Weeds. FRONTIERS IN ENVIRONMENTAL SCIENCE, v. 6, MAR 14 2018. (15/15617-9, 14/20286-9)

CAMPOS, ESTEFANIA V. R.; OLIVEIRA, JHONES L.; ZAVALA-BETANCOURT, SARA A.; LEDEZMA, ANTONIO S.; ARIAS, EDUARDO; MOGGIO, IVANA; ROMERO, JORGE; FRACETO, LEONARDO F.. Development of stained polymeric nanocapsules loaded with model drugs: Use of a fluorescent poly(phenyleneethynylene). COLLOIDS AND SURFACES B-BIOINTERFACES, v. 147, p. 442-449, NOV 1 2016. (14/20286-9, 15/15617-9, 14/20273-4)

CAMPOS, ESTEFANIA V. R.; PROENCA, PATRICIA L. F.; OLIVEIRA, JHONES L.; BAKSHI, MANSI; ABHILASH, P. C.; FRACETO, LEONARDO F.. Use of botanical insecticides for sustainable agriculture: Future perspectives. ECOLOGICAL INDICATORS, v. 105, p. 483-495, OCT 2019. (14/20273-4, 15/15617-9, 14/20286-9)

CAMPOS, ESTEFNIA V. R.; OLIVEIRA, JHONES L.; FRACETO, LEONARDO F.. Poly(ethylene glycol) and Cyclodextrin-Grafted Chitosan: From Methodologies to Preparation and Potential Biotechnological Applications. RONTIERS IN CHEMISTR, v. 5, p. 15-pg., 2017-11-07. (14/20286-9, 15/15617-9, 14/20273-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

OLIVEIRA, Jhones Luiz de. Development of modified release systems based on zein and chitosan for botanical repellents aiming whitefly (Bemisia tabaci) control in different crops. 2018. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Instituto de Ciência e Tecnologia. Sorocaba Sorocaba.