Metaqua: metabolite/metabolomic profiling in aquaculture research with a view to maintaining food safety / security and animal / human health

• Grant number: 14/50755-0
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2016
• End date: January 31, 2018
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Agreement: Queen's University of Belfast
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Jonas Augusto Rizzato Paschoal
• Grantee: Jonas Augusto Rizzato Paschoal
• Principal researcher abroad: Mark Mooney
• Institution abroad: Queen's University Belfast, Northern Ireland
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 12/18334-0 - Veterinary drug residues in food: multiclass analytical methods employing LC-MS/MS, exposition data and residual depletion study, AP.JP

Abstract

The METAQUA partnership will seek to form a new interdisciplinary collaborative partnership between Dr Mark Mooney (QUB, UK) and Dr Jonas Paschoal (USP, Brazil) using the complementary expertise and analytical capabilities available to these researchers to explore the potential of metabolite/metabolomic profiling to assess aquaculture responses to chemical exposure with a view to maintaining food safety/security and animal/human health. Metabolomics research focuses on the large scale and high-throughput profiling of small molecules (metabolites) in biological matrices using advanced mass spectrometry techniques. Due to the myriad of organs and metabolic pathways acted upon by exogenously administered agents, either through primary interaction or secondary metabolic effects, metabolomics has the capability to assess physiological and biological responses in animals following chemical exposure. This partnership will use researcher exchange missions to plan and develop a joint research programme to examine the chemical metabolite and biological metabolome responses to drug exposure in fish. The overall objective of METAQUA will be to frame the groundwork to prepare collaborative applications between QUB and USP to attract BBSRC-Brazil (FAPESP) funding of new aquaculture based research programmes. The proposed area for collaboration will seek to exploit the synergy between the BBSRC and FAPESP in a key strategic priority of both bodies i.e. "Agriculture and Food Security”. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VELLOSA PORTELA, ANA CAROLINA; FERNANDES SILVEIRA, JULIANA GRELL; DAMACENO, MARINA ALVES; BALDO DA SILVA, AGNALDO FERNANDO; DE JESUS, RAPHAEL BARBETTA; PILARSKI, FABIANA; GADAJ, ANNA; MOONEY, MARK H.; RIZZATO PASCHOAL, JONAS AUGUSTO. Food safety evaluation for the use of albendazole in fish: residual depletion profile and withdrawal period estimation. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure, v. 37, n. 4, FEB 2020. (12/18334-0, 16/16593-9, 14/50755-0)

NETO, PEDRO FRACCAROLLI; BALDO DA SILVA, AGNALDO FERNANDO; MORO, EVANDRO BILHA; PILARSKI, FABIANA; DE FREITAS, OSVALDO; MOONEY, MARK H.; RIZZATO PASCHOAL, JONAS AUGUSTO. Emamectin benzoate in tilapia: Alternative method for drug incorporation into feed and associated residual depletion study. Food Research International, v. 119, p. 524-529, MAY 2019. (12/18334-0, 14/50755-0)