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Sedentary behaviour and arterial dysfunction in chronic post-stroke subjects

Abstract

Post-stroke disability leads to a sedentary lifestyle, increasing the risk of developing a new cerebrovascular and/or cardiac events. Arterial dysfunction plays an important role in the pathophysiology of these events. Endothelial dysfunction, arterial stiffness and autonomic nervous system dysfunction are associated with increased risk of cardiovascular disease, morbidity and mortality. and there seems to be correlation among these variables. However, information about the impact of stroke on these variables and how they are affected by a sedendaty behavior in post-stroke patients is insufficient. Therefore, the purpose of this project is to characterize arterial function with sedentary time among hemiparetic patients after stroke in chronic stage of recovery. To do that, a cross-sectional study will be conducted with 30 patients in chronic phase of stroke (at least 6 months post-stroke) and 30 healhty subjects matched by age, sex, body mass index. The assessments will be carried out in 2 days with one week between each day. On the first day, the sensory-motor impairment of post-stroke patients will be assessed, and the 6-minute walk test and the 10-meter walk test will be performed. Finally, the accelerometer will be placed on the ankle of the volunteer who should use it uninterruptedly for 7 days. On the second day, the accelerometer will be removed, autonomic nervous system function, arterial stiffness and endothelial fuction will be evaluated. The data will be statistically analyzed with normality and homogeneity tests to define the use of parametric or non-parametric analysis. Independent Student's t-test or Mann-Whitney test will be used to compare the differences between groups, and Pearson's correlation coefficient or Spearman's correlation coeficiente will be used to correlate the data. (AU)

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VEICULO: TITULO (DATA)
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Scientific publications (14)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MOREIRA DA SILVA, ERIKA SHIRLEY; SANTOS, GABRIELA LOPES; CATAI, APARECIDA MARIA; BORSTAD, ALEXANDRA; DUARTE FURTADO, NATALIA PEREIRA; VERZOLA ANICETO, ISABELA ARRUDA; RUSSO, THIAGO LUIZ. Effect of aerobic exercise prior to modified constraint-induced movement therapy outcomes in individuals with chronic hemiparesis: a study protocol for a randomized clinical trial. BMC Neurology, v. 19, n. 1, . (17/13655-6, 17/25185-4)
GARCIA, LUCCAS CAVALCANTI; ALCANTARA, CAROLINA CARMONA; SANTOS, GABRIELA LOPES; ALMEIDA MONCAO, JOAO VICTOR; RUSSO, THIAGO LUIZ. Cryotherapy Reduces Muscle Spasticity But Does Not Affect Proprioception in Ischemic Stroke A Randomized Sham-Controlled Crossover Study. AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, v. 98, n. 1, p. 51-57, . (17/13655-6, 13/25805-1, 14/25845-6)
ALCANTARA, CAROLINA CARMONA; BLANCO, JULIA; DE OLIVEIRA, LUCILENE MARIA; SAVIO RIBEIRO, PAULA FERNANDA; HERRERA, ESPERANZA; NAKAGAWA, THERESA HELISSA; REISMAN, DARCY S.; MICHAELSEN, STELLA MARIS; GARCIA, LUCCAS CAVALCANTI; RUSSO, THIAGO LUIZ. Cryotherapy reduces muscle hypertonia, but does not affect lower limb strength or gait kinematics post-stroke: a randomized controlled crossover study. Topics in Stroke Rehabilitation, v. 26, n. 4, p. 267-280, . (17/13655-6, 13/25805-1, 14/25845-6)
FERNANDA GARCIA-SALAZAR, LUISA; MATOS RIBEIRO, JEAN ALEX; EMANUEL CUNHA, JONATHAN; MARCIA MATTIELLO, STELA; LUIZ RUSSO, THIAGO. Serum activity of matrix metalloproteinase-2 and-9 is increased in chronic post-stroke individuals: a cross-sectional exploratory study. Topics in Stroke Rehabilitation, . (17/13655-6)
ALCANTARA, CAROLINA C.; GARCIA-SALAZAR, LUISA F.; SILVA-COUTO, MARCELA A.; SANTOS, GABRIELA L.; REISMAN, DARCY S.; RUSSO, THIAGO L.. Post-stroke BDNF Concentration Changes Following Physical Exercise: A Systematic Review. FRONTIERS IN NEUROLOGY, v. 9, . (17/13655-6, 13/25805-1, 15/19197-4, 15/21695-2, 14/25845-6)
GARCIA OLIVEIRA, SIMONE; LOURENCO NOGUEIRA, SAMUEL; ALEX MATOS RIBEIRO, JEAN; CARNAZ, LETICIA; REGINA ROCHA URRUCHIA, VITORIA; ALCANTARA, CAROLINA CARMONA; RUSSO, THIAGO L.. oncurrent validity and reliability of an activity monitoring for rehabilitation (AMoR) platform for step counting and sitting/lying time in post-stroke individual. Topics in Stroke Rehabilitation, v. 29, n. 2, . (13/25805-1, 17/13655-6, 19/25569-2)
Y.C. ESTRADA-BONILLA; P.A.T.S. CASTRO; G.L.F. LUNA; A.B.A. SOUZA; G.S. SANTOS; T.F. SALVINI; A.M.O. LEAL; T.L. RUSSO. Reaching task performance is associated to neuromuscular junction adaptations in rats with induced diabetes mellitus. Brazilian Journal of Medical and Biological Research, v. 53, n. 7, . (17/13655-6, 13/21621-3)
MATOS RIBEIRO, JEAN ALEX; DA SILVA OLIVEIRA, ACSON GUSTAVO; DI THOMMAZO-LUPORINI, LUCIANA; MONTEIRO, CLARA ITALIANO; OCAMOTO, GABRIELA NAGAI; CATAI, APARECIDA MARIA; BORGHI-SILVA, AUDREY; PHILLIPS, SHANE A.; RUSSO, THIAGO LUIZ. Underlying mechanisms of oxygen uptake kinetics in chronic post-stroke individuals: A correlational, cross-sectional pilot study. PLoS One, v. 15, n. 11, . (17/13655-6, 17/22173-5)
SILVA-COUTO, M. A.; SIQUEIRA, A. A. G.; SANTOS, GABRIELA L.; RUSSO, THAIGO L.. Ankle torque steadiness and gait speed after a single session of robot therapy in individuals with chronic hemiparesis: a pilot study. Topics in Stroke Rehabilitation, v. 26, n. 8, . (17/13655-6, 14/25845-6)
RIBEIRO, JEAN A. M.; OLIVEIRA, SIMONE G.; DI THOMMAZO-LUPORINI, LUCIANA; MONTEIRO, I, CLARA; PHILLIPS, SHANE A.; CATAI, APARECIDA M.; BORGHI-SILVA, AUDREY; RUSSO, THIAGO L.. Energy Cost During the 6-Minute Walk Test and Its Relationship to Real-World Walking After Stroke: A Correlational, Cross-Sectional Pilot Study. PHYSICAL THERAPY, v. 99, n. 12, p. 1656-1666, . (17/13655-6)
GARCIA-SALAZAR, LUISA FERNANDA; RIBEIRO, JEAN ALEX MATOS; SAADE-PACHECO, CASSIA REGINA; MATTIELLO, STELA MARCIA; CATAI, APARECIDA MARIA; GARCIA-ARAUJO, ADRIANA SANCHES; RUSSO, THIAGO LUIZ. Adiponectin Concentration and Chronic Stroke Individuals, Associations with Body Composition, Physical Activity Levels and Lipid Profile: A Cross-Sectional Explorative Study. JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v. 30, n. 10, . (17/13655-6)
RIBEIRO, JEAN ALEX MATOS; GARCIA-SALAZAR, LUISA FERNANDA; SAADE-PACHECO, CASSIA REGINA; SILVA, ERIKA SHIRLEY MOREIRA; OLIVEIRA, SIMONE GARCIA; SILVEIRA, ANA FLAVIA; GARCIA-ARAUJO, ADRIANA SANCHES; RUSSO, THIAGO LUIZ. Prognostic molecular markers for motor recovery in acute hemorrhagic stroke: A systematic review. Clinica Chimica Acta, v. 522, p. 45-60, . (17/13655-6, 17/25185-4)
RIBEIRO, JEAN ALEX MATOS; OLIVEIRA, SIMONE GARCIA; OCAMOTO, GABRIELA NAGAI; THOMMAZO-LUPORINI, LUCIANA DI; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY; PHILLIPS, SHANE A.; BILLINGER, SANDRA A.; RUSSO, THIAGO LUIZ. Hemispheric lateralization, endothelial function, and arterial compliance in chronic post-stroke individuals: A cross-sectional exploratory study. International Journal of Neuroscience, v. N/A, p. 11-pg., . (17/13655-6, 17/22173-5)
GARCIA OLIVEIRA, SIMONE; LOURENCO NOGUEIRA, SAMUEL; ALEX MATOS RIBEIRO, JEAN; CARNAZ, LETICIA; REGINA ROCHA URRUCHIA, VITORIA; ALCANTARA, CAROLINA CARMONA; RUSSO, THIAGO L.. Concurrent validity and reliability of an activity monitoring for rehabilitation (AMoR) platform for step counting and sitting/lying time in post-stroke individuals. Topics in Stroke Rehabilitation, v. 29, n. 2, p. 11-pg., . (19/25569-2, 13/25805-1, 17/13655-6)