Canine visceral leishmaniasis: abdominal imaging study of the appendicular skeleton in dogs naturally infected

• Grant number: 12/01526-3
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: September 01, 2012
• End date: November 30, 2013
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Maria Jaqueline Mamprim de Arruda Monteiro
• Grantee: Alexandre Redson Soares da Silva
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Leishmaniasis is a worldwide disease of zoonotic potential, which affects humans and a variety of domestic and wild animals, with different clinical presentations. Caused by a protozoan of the genus Leishmania spp., And has as an etiologic agent in Brazil, Leishmania (Leishmania) chagasi. In the Brazilian federation, the importance of visceral leishmaniasis, is its high incidence and geographical distribution. What makes the domestic environment, dogs and hosts important sources of infection for the vectors for the high infectivity. Infected dogs are epidemiologically considered more important than the disease in humans for several reasons: high prevalence, incidence and a large contingent primary enzootic of parasitism in the skin. The clinical diagnosis is still a challenge for health profissinais because of the wide variety of signs and symptoms as well as the high percentage of asymptomatic animals. However, affected animals usually develop a chronic systemic disease, and may have specific clinical manifestations and varied. The analysis associated imaginológica (ultrasound, digital radiography and computed tomography) of dogs with visceral leishmaniasis assists in the investigation of disease, however, reports are scarce and often controversial. Given the importance of visceral leishmaniasis in public health because the disease has become the emerging state of São Paulo, this project aims to assess the contribution of different modes of imaging, in dogs naturally affected by visceral leishmaniasis. The digital radiographic and computed tomography of the appendicular skeleton is comparative and represents the continuity of the research developed in the master's scholarship in order to investigate the detection of lesions of the disease early. Report possible abdominal ultrasound changes found in these animals as a contribution to diagnosis, it is not yet veterinary literature citations. The study aims to provide subsidies for the diagnosis of clinical disease for veterinarians who work in areas endemic for the disease in dogs and humans. For this, we used 50 dogs naturally infected with serologic or parasitologic positive for Leishmania spp., Referred to the Veterinary Hospital of Universidade Paulista, the city of Bauru, São Paulo, during the period from March 2012 to March 2013.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SILVA, ALEXANDRE REDSON S.; OLIVEIRA, HUGO S.; GOMES, ANA AMELIA D.; BESERRA, HUGO ENRIQUE O.; SILVA, JEANA P.; SANTOS-DONI, THAIS R.; TSUNEMI, MIRIAM H.; MARCONDES, MARY; RAHAL, SHEILA C.; MAMPRIM, MARIA J.. Joint involvement in canine visceral leishmaniasis: Orthopedic physical examination, radiographic and computed tomographic findings. Veterinary Parasitology, v. 299, NOV 2021. (12/02484-2, 12/01526-3, 18/21048-5)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SILVA, Alexandre Redson Soares da. Canine visceral leishmaniasis: imaging study in naturally infected dogs. 2014. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Medicina Veterinária e Zootecnia. Botucatu Botucatu.