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Effect of composite and bioactive niobophosphate glass on biofilm formation

Grant number: 12/18220-4
Support Opportunities:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): January 30, 2013
Effective date (End): January 29, 2014
Field of knowledge:Health Sciences - Dentistry - Endodontics
Principal Investigator:Giulio Gavini
Grantee:Ceci Nunes Carvalho
Supervisor: Markus Paavo Päiviö Haapasalo
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: University of British Columbia, Vancouver (UBC), Canada  
Associated to the scholarship:11/18967-0 - Development and characterization of a composite-based bioactive glass Niobium/Phosphate and gutta-percha for endodontic use: Analysis of bond strength to dentin and nanoleakage., BP.DR


The aim of this study is to develop and characterize a composite for endodontic filling and evaluate the bond strength to root dentin of an experimental composite, a commercial gutta-percha (Endosequence BC) and conventional gutta-percha associated with AH Plus sealer, through the μpush-out test. The analysis of fracture patterns will be held with scanning eletron microscopy (SEM). EDX analysis and SEM-EDS will be held to verify the composition of the tested materials. The influence of the experimental composites and different types of gutta percha in adherence and biofilm formation by oral bacteria staining with Live / Dead using a confocal laser microscope will be assessed. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CARVALHO, C. N.; MARTINELLI, J. R.; BAUER, J.; HAAPASALO, M.; SHEN, Y.; BRADASCHIA-CORREA, V.; MANSO, A. P.; GAVINI, G.. Micropush-out dentine bond strength of a new gutta-percha and niobium phosphate glass composite. International Endodontic Journal, v. 48, n. 5, p. 451-459, . (12/18220-4, 11/18967-0)
CARVALHO, C. N.; WANG, Z.; SHEN, Y.; GAVINI, G.; MARTINELLI, J. R.; MANSO, A.; HAAPASALO, M.. Comparative analyses of ion release, pH and multispecies biofilm formation between conventional and bioactive gutta-percha. International Endodontic Journal, v. 49, n. 11, p. 1048-1056, . (12/18220-4)
BOSIO MENESES, CLAUDIA CAROLINE; OLIVI, LUCAS TOFANELLO; CARVALHO, CECI NUNES; GAVINI, GIULIO; SIPERT, CARLA RENATA. Cytotoxic Effect of Niobium Phosphate Glass-based Gutta-Percha Points on Periodontal Ligament Fibroblasts In Vitro. JOURNAL OF ENDODONTICS, v. 46, n. 9, p. 5-pg., . (12/18220-4, 17/00643-0, 17/01737-8, 16/13944-5)

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