Evaluation of the permeability of experimental resin infiltrants on the treatment of artificial white spot lesions

• Grant number: 13/23310-5
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: February 03, 2014
• End date: June 02, 2014
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Linda Wang
• Grantee: Maria Cristina Carvalho de Almendra Freitas
• Supervisor: Anuradha Prakki
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Institution abroad: University of Toronto (U of T), Canada
• Associated to the scholarship: 12/18579-2 - Effect of a resin infiltrant on white spot lesions treatment: in vitro, in situ and in vivo analyses, BP.DR

Abstract

A resinous agent for the treatment of carious white spot lesions has been used with the potential to infiltrate tooth tissue, filling the pores of enamel affected by the lesion and preventing its progression. Currently, this resin infiltrant is commercially available by just one product: Icon®. This project aims to compare the permeability of Icon® and experimental infiltrants on artificial caries lesions by confocal laser scanning microscopy (CLSM) and measurement of its depth permeability. Artificial caries lesions will be produced in 120 specimens of bovine flat enamel by pH cycling. Specimens will be treated with either the Icon® infiltrant or experimental products (n= 10). After treatment, specimens shall be prepared for evaluation of the permeability through CLSM. The penetration of infiltrants will be defined by the distance from the surface to the deepest point labeled with the fluorescent dye Rhodamine B, which will be incorporated prior to the infiltrants. Data will be collected and statistically analyzed according to the distribution to be verified. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

WANG, LINDA; CARVALHO DE ALMENDRA FREITAS, MARIA CRISTINA; PRAKKI, ANURADHA; MOSQUIM, VICTOR; MIRANDA GONZALEZ, ALEJANDRA HORTENCIA; RIOS, DANIELA; HONORIO, HEITOR MARQUES. Experimental self-etching resin infiltrants on the treatment of simulated carious white spot lesions. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 113, JAN 2021. (12/18579-2, 12/13160-3, 13/23310-5)