Antiparasitic in Brazilian soils: study of sorption, desorption and degradation

• Grant number: 13/25670-9
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: March 01, 2014
• End date: February 28, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Susanne Rath
• Grantee: Fabricio de Oliveira Ferreira
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/09543-7 - Residues of veterinary drugs in the environment, AP.TEM

Abstract

Veterinary drugs, in particular the class of antiparasitic drugs have been widely employed in the livestock to ensure animal health and an increase in the production of food of animal origin. Besides the need to control these drugs, there is also the problem associated with the environmental impact they cause when they are excreted by treated animals. While using these drugs bring benefits to livestock, aquaculture and agriculture, they may cause serious risks to water, soil, plants, food, land and aquatic organisms, since a vast majority of chemicals entering the environment in its metabolized form or otherwise, through the feces and urine of the animals. Once present in the field, drugs with high sorption capacity will tend to accumulate in soils and sediments. Conversely, compounds with low sorption capacity will be leached and may contaminate groundwater and surface water. Studies on the behavior of veterinary drugs in soils and the development of methods for their determination in this type of matrix, are still scarce. The use of antiparasitic drugs, in particular the avermectins, has been widely used by livestock farmers in Brazil and the country has been faced several embargoes related to contamination of animal products origin above the maximum permitted residue. In fact , there is an inherent need to assess the fate of these compounds in the environment . Therefore, this project aims to assess the mobility of avermectins in different soils through studies of sorption and desorption, as well as evaluate aerobic and anaerobic degradation of avermectins in soils. Still, aims the synthesis of a molecularly imprinted polymer for the avermectins so that it can be used for sample preparation prior to quantification by HPLC and UPLC. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERREIRA, FABRICIO DE OLIVEIRA; PORTO, RAFAEL SILVEIRA; RATH, SUSANNE. Aerobic dissipation of avermectins and moxidectin in subtropical soils and dissipation of abamectin in a field study. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, v. 183, NOV 15 2019. (18/03571-2, 13/09543-7, 13/25670-9)

RATH, SUSANNE; FOSTIER, ANNE HELENE; PEREIRA, LEANDRO ALVES; DIONISO, ANDREZA CAMILOTTI; FERREIRA, FABRICIO DE OLIVEIRA; DORETTO, KEITY MARGARETH; PERUCHI, LIVIA MANIERO; VIERA, ALESSANDRA; DE OLIVEIRA NETO, ODILON FRANCA; DAL BOSCO, SANDRA MARIA; et al. Sorption behaviors of antimicrobial and antiparasitic veterinary drugs on subtropical soils. Chemosphere, v. 214, p. 111-122, JAN 2019. (12/01767-0, 14/16995-4, 13/25670-9, 13/09543-7, 18/03571-2)

FERREIRA, FABRICIO DE OLIVEIRA; RODRIGUES-SILVA, CAIO; RATH, SUSANNE. On-line solid-phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry for the determination of avermectins and milbemycin in soils. Journal of Chromatography A, v. 1471, p. 118-125, NOV 4 2016. (13/09543-7, 14/16622-3, 13/25670-9)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FERREIRA, Fabricio de Oliveira. Antiparasitics in brazilian soils: sorption, desorption and dissipation study. 2017. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Instituto de Química Campinas, SP.