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Arrabidaea spp: studies to make possible the development of phytomedicines

Grant number: 14/03728-8
Support type:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): July 15, 2014
Effective date (End): December 31, 2014
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Principal Investigator:Wagner Vilegas
Grantee:Cláudia Quintino da Rocha
Supervisor abroad: Jean-Luc Wolfender
Home Institution: Universidade Estadual Paulista (UNESP). Campus Experimental do Litoral Paulista. São Vicente , SP, Brazil
Local de pesquisa : Université de Genève, Switzerland  
Associated to the scholarship:13/06188-1 - Arrabidaea sp: studies to enable the development of phytomedicines, BP.PD


The proposed postdoctoral is linked to the Thematic Project FAPESP: "Standardization herbal medicines for the treatment of chronic diseases "intends to conduct a study with Arrabidaea brachypoda species, to enable the development of a phytomedimedicine according to the requirements of current legislation. In a second moment, a profundidade in pharmacological tests with compounds already isilados of Arrabidaea brachypoda, since in previous project these same compounds showed extremely promising potential for the development of PPPs, with activities in Malaria, Chagas and Leischmania. With the results of this survey anteriorly, three patents have been deposited at the National Institute for Research and Innovation (INPI) and the Swiss Agency for Innovation. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA ROCHA, CLAUDIA QUINTINO; DE-FARIA, FELIPE MEIRA; MARCOURT, LAURENCE; EBRAHIMI, SAMAD NEJAD; KITANO, BRUNA TIEMI; GHILARDI, AMANDA FRANCESCHINI; FERREIRA, ANDERSON LUIZ; DE ALMEIDA, ANA CRISTINA ALVES; DUNDER, RICARDO JOSE; MONTEIRO SOUZA-BRITO, ALBA REGINA; HAMBURGER, MATTHIAS; VILEGAS, WAGNER; QUEIROZ, EMERSON FERREIRA; WOLFENDER, JEAN-LUC. Gastroprotective effects of hydroethanolic root extract of Arrabidaea brachypoda: Evidences of cytoprotection and isolation of unusual glycosylated polyphenols. Phytochemistry, v. 135, p. 93-105, MAR 2017. Web of Science Citations: 10.

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