Allelopathic potential of Mimosa spp. in the development of phytomedicines

• Grant number: 17/01341-7
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: September 15, 2017
• End date: September 14, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Wagner Vilegas
• Grantee: Marcelo José Dias Silva
• Supervisor: Francisco Antonio Macias Dominguez
• Host Institution: Instituto de Biociências (IB-CLP). Universidade Estadual Paulista (UNESP). Campus Experimental do Litoral Paulista. São Vicente , SP, Brazil
• Institution abroad: Universidad de Cádiz, Puerto Real (UCA), Spain
• Associated to the scholarship: 15/21479-8 - Standardization of plant extracts of Mimosa spp. development phytomedicines, BP.PD

Abstract

The use of plants of the Brazilian flora as a source of active principles has been increasingly effective in the search for medicines. However, little has been done to transform this potential into new product development and patents. The present postdoctoral proposal will continue the studies of the thematic project "Standardized herbal medicine for the treatment of chronic diseases" of FAPESP, with the species Mimosa caesalpiniifolia in the sense of developing a phytotherapeutic (s). Previous trials have shown promising results for the development of phytomedications, with anti-inflammatory and antifungal activity. In addition to supporting activities and research conducted internally, a partnership with the University of Cadiz (UCA) of Spain will allow to evaluate the potential allelopathic extracts / pure compounds of Mimosa caesalpiniifolia in the study of the phytotoxic activity the research group has different techniques and domain In "Studies in allelopathic plants and superior microorganisms" that in Brazil these studies are scarce. Allelopathy is a science that studies the interactions between plants and organisms in their environment mediated by chemical agents is a valuable source as medicinal potential. The group will enrich and complement the studies initially proposed by the thematic project and the present postdoctoral project. (AU)