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Effect of infiltrant on microhardness and roughness of white spot lesions after different challenges

Grant number: 14/25760-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2015
Effective date (End): December 31, 2015
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal researcher:Ticiane Cestari Fagundes
Grantee:Emerson Yoshio Neres
Home Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil


The white spot lesion is related to the mineral loss of enamel and is characterized by early manifestation of dental caries. The aim of this study is to assess white spot lesions after application of an infiltrating and submitted to challenges such as artificial brushing and pH cycling. Forty discs from bovine teeth will be divided into four groups with 10 specimens each: demineralized enamel, simulating artificial white spot lesion (negative control - GI), infiltrated demineralized enamel (GII); infiltrated demineralized enamel subjected to brushing (GIII); and infiltrated demineralized enamel subjected to pH cycling (GIV). Each specimen will have the own sound enamel as positive control. After the different challenges, the specimens will be evaluated for microhardness and roughness. The data will be submitted to ANOVA and Tukey's test for multiple comparisons (p d 0.05).

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
NERES, E. Y.; MODA, M. D.; CHIBA, E. K.; BRISO, A. L. F.; PESSAN, J. P.; FAGUNDES, T. C. Microhardness and Roughness of Infiltrated White Spot Lesions Submitted to Different Challenges. Operative Dentistry, v. 42, n. 4, p. 428-435, JUL-AUG 2017. Web of Science Citations: 4.

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