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Carbapenemases detection and identification in Klebsiella pneumoniae isolates from patients admitted to a University Hospital of Paraná State, Brazil

Grant number: 15/10403-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2015
Effective date (End): December 31, 2016
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:André Pitondo da Silva
Grantee:Guilherme Bartolomeu Gonçalves
Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:13/22581-5 - Study of pathogenic mechanisms and correlation with antimicrobial resistance of Klebsiella pneumoniae from Brazil and other countries across five continents, AP.JP

Abstract

Carbapenemase-producing bacteria, especially Klebsiella pneumoniae strains, have been commonly associated with hospital outbreaks, leading to high mortality due to few therapeutic options available for admitted patients. Therefore, studies investigating the prevalence and types of carbapenemases in Klebsiella pneumoniae from distinct Brazilian regions are extremely relevant. The aim of this study is to investigate the presence of carbapenemases in K. pneumoniae isolated from patients hospitalized at a university hospital of Paraná State, Brazil, as well as characterizing the genetic relationship among the isolates by ERIC-PCR. (AU)

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