Electrode carbon vitreous modified with titanium dioxide nanotubes and tapioca film for detection of hormone estradiol

• Grant number: 16/04743-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): June 01, 2016
• Effective date (End): December 31, 2016
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Bruno Campos Janegitz
• Grantee: Gabriela Carolina Mauruto de Oliveira
• Host Institution: Centro de Ciências Agrárias (CCA). Universidade Federal de São Carlos (UFSCAR). Araras , SP, Brazil

Abstract

The interest in the development of sensors has grown over the years, since it can be produced low cost devices that provide accurate answers. The use of metal nanoparticles in the construction of modified electrodes has extended due to their electrochemical characteristics that aid in better sensitivity. In this context, TiO2 nanotubes are materials that exhibit thermodynamic, electrical and chemical characteristics that are interesting for its use in electrochemical sensors. Tapioca is a material with high load of starch and intrinsic characteristics that can provide nanostructured films, hence, it can be used for attaching nanomaterials in modified electrodes. Electrodes based nanomaterials have been developed for the detection of various analyses, including hormones. Both in environmental and medical field, the study and detection of hormones are important. Estradiol presents is estrogen that can be related with a variety of diseases, so, the goal of this project is the development of a modified electrochemical sensor with TiO2 nanotubes using tapioca as a sticky biofilm, for the detection of 17²-estradiol hormone in various biological matrices, such as urine, serum and water samples.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PEREIRA, TAMIRES DOS SANTOS; MAURUTO DE OLIVEIRA, GABRIELA C.; SANTOS, FABRICIO APARECIDO; RAYMUNDO-PEREIRA, PAULO A.; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO CAMPOS. Use of zein microspheres to anchor carbon black and hemoglobin in electrochemical biosensors to detect hydrogen peroxide in cosmetic products, food and biological fluids. Talanta, v. 194, p. 737-744, MAR 1 2019. (17/17572-8, 16/01919-6, 13/14262-7, 16/18270-2, 15/19099-2, 16/04743-6)

MAURUTO DE OLIVEIRA, GABRIELA C.; DE PALMA, ELISANGELA P.; KUNITA, MARCOS H.; MEDEIROS, ROBERTA ANTIGO; DE MATOS, ROBERTO; FRANCISCO, KELLY ROBERTA; JANEGITZ, BRUNO C.. Tapioca Biofilm Containing Nitrogen-doped Titanium Dioxide Nanoparticles for Electrochemical Detection of 17-beta Estradiol. Electroanalysis, v. 29, n. 11, p. 2638-2645, NOV 2017. (16/04743-6, 15/19099-2)