Influence of beta-alanine supplementation associated with high-intensity interval training on performance of repeated sprints.

• Grant number: 16/02683-6
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: July 01, 2016
• End date: May 28, 2018
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Alessandro Moura Zagatto
• Grantee: Fabio Milioni
• Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil
• Associated scholarship(s): 16/26281-4 - TIME-COURSE OF PERFORMANCE AND NEUROMUSCULAR RECOVERY FROM INTERMITTENT SPRINT EFFORTS., BE.EP.DR

Abstract

The main objective of this project is to verify the possible influences of the association between supplementation of ²-alanine and high intensity interval training (HIIT) on repeated sprint performance. 20 young men will participate in the study that will be conducted in a randomized, double-blind design. They will be randomly divided into two groups (G² - ²-alanine supplementation; GP - placebo supplementation). The volunteers will be evaluated at three different moments; before the start of HIIT (4 weeks) before the beginning of HIIT associated with supplementation (6 weeks) and after training period. Previously the eavluations will be performed a nutritional record of three days to control the energy consumption of the participants. The evaluations will consist of: Day 1 - an incremental test until exhaustion; Day 2 - three maximum jump (counter moviment jump) before and immediately after two bouts of six 35-m sprints with 10 s rest between sprints and 4 min rest between bouts; Day 3 - time to exhaustion at 115% of intensity attained to maximum oxygen uptake. The tests will be performed on isolated days and separated by 48 hours. Previously and immediately after the procedures of the 1st and 2nd days will be performed neuromuscular evaluations that consist of maximum isometric knee extension jointly the Twitch Interpolation technique. Volunteers will train for 10 weeks, and during the last six weeks of training will be associated with administration of 6.4 g/day of ²-alanine or placebo (dextrose). Prior to the start of supplementation and imediatly after the end of the protocol, the volunteers will be submitted to muscle biopsy and the sample of muscle tissue will be used to determine the content of intramuscular carnosine, in vitro buffering capacity and content/activity of key enzymes.

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MALTA, ELVIS DE SOUZA; BONETTI DE POLI, RODRIGO ARAUJO; PINHEIRO BRISOLA, GABRIEL MOTTA; MILIONI, FABIO; MIYAGI, WILLIAN EIJI; MACHADO, FABIANA ANDRADE; ZAGATTO, ALESSANDRO MOURA. Acute LED irradiation does not change the anaerobic capacity and time to exhaustion during a high-intensity running effort: a double-blind, crossover, and placebo-controlled study. Lasers in Medical Science, v. 31, n. 7, p. 1473-1480, SEP 2016. (16/02683-6, 15/05012-2, 13/12940-8)

MILIONI, FABIO; DE MELLO LEITE, JORGE VIEIRA; BENEKE, RALPH; BONETTI DE POLI, RODRIGO ARAUJO; PAPOTI, MARCELO; ZAGATTO, ALESSANDRO MOURA. Table tennis playing styles require specific energy systems demands. PLoS One, v. 13, n. 7, JUL 18 2018. (16/02683-6, 16/17836-2)

MILIONI, FABIO; ZAGATTO, ALESSANDRO MOURA; BARBIERI, RICARDO AUGUSTO; ANDRADE, VITOR LUIZ; DOS SANTOS, JULIO WILSON; GOBATTO, CLAUDIO ALEXANDRE; DA SILVA, ADELINO S. R.; PEREIRA SANTIAGO, PAULO ROBERTO; PAPOTI, MARCELO. Energy Systems Contribution in the Running-based Anaerobic Sprint Test. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v. 38, n. 3, p. 226-232, MAR 2017. (16/02683-6)

MILIONI, FABIO; BONETTI DE POLI, RODRIGO ARAUJO; SAUNDERS, BRYAN; GUALANO, BRUNO; DA ROCHA, ALISSON L.; RAMOS DA SILVA, ADELINO SANCHEZ; GUERRERO MULLER, PAULO DE TARSO; ZAGATTO, ALESSANDRO MOURA. Effect of beta-alanine supplementation during high-intensity interval training on repeated sprint ability performance and neuromuscular fatigue. Journal of Applied Physiology, v. 127, n. 6, p. 1599-1610, DEC 2019. (16/11076-6, 16/50438-0, 16/17836-2, 16/02683-6)

MILIONI, FABIO; AZEVEDO, RAFAEL A.; ZAGATTO, ALESSANDRO M.; MILLET, GUILLAUME Y.. Time Course of Recovery after Cycling Repeated Sprints. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 53, n. 2, p. 413-420, FEB 2021. (16/26281-4, 16/02683-6)

AZEVEDO, RAFAEL A.; MILIONI, FABIO; MURIAS, JUAN M.; BERTUZZI, ROMULO; MILLET, GUILLAUME Y.. Dynamic Changes of Performance Fatigability and Muscular O-2 Saturation in a 4-km Cycling Time Trial. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 53, n. 3, p. 613-623, MAR 2021. (16/26281-4, 16/02683-6, 17/22053-0)

REDKVA, PAULO EDUARDO; MIYAGI, WILLIAN EIJI; MILIONI, FABIO; ZAGATTO, ALESSANDRO MOURA. Anaerobic capacity estimated by the sum of both oxygen equivalents from the glycolytic and phosphagen pathways is dependent on exercise mode: Running versus cycling. PLoS One, v. 13, n. 9, SEP 13 2018. (14/02829-5, 13/12940-8, 16/02683-6)

MILIONI, FABIO; VIEIRA, LUIZ H. P.; BARBIERI, RICARDO A.; ZAGATTO, ALESSANDRO M.; NORDSBORG, NIKOLAI B.; BARBIERI, FABIO A.; DOS-SANTOS, JOLIOW.; SANTIAGO, PAULO R. P.; PAPOTI, MARCELO. Futsal Match-Related Fatigue Affects Running Performance and Neuromuscular Parameters but Not Finishing Kick Speed or Accuracy. FRONTIERS IN PHYSIOLOGY, v. 7, NOV 7 2016. (13/08302-6, 16/02683-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MILIONI, Fabio. Influência da suplementação de β-alanina associada ao treinamento intervalado de alta intensidade no desempenho de sprints repetidos. 2018. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Ciências. Bauru Bauru.