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Production of vitamin B12 microcapsules using co-extrusion followed by fluidized bed dehydration

Grant number: 16/16692-7
Support type:Scholarships abroad - Research Internship - Scientific Initiation
Effective date (Start): October 01, 2016
Effective date (End): January 31, 2017
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Engineering
Principal researcher:Carmen Sílvia Fávaro Trindade
Grantee:Marcella Chalella Mazzocato
Supervisor abroad: Denis Poncelet
Home Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
Research place: Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation de Nantes-Atlantique, France  
Associated to the scholarship:15/19376-6 - Study of the physical-chemical characteristics and solid lipid microparticules stability containing vitamin B12 produced by spray chilling technique, BP.IC


Vitamin B12, or Cyanocobalamin, is a water-soluble substance produced by some microorganisms. It occurs in small amounts primarily in animal food and some leguminous plant. The low concentration of vitamin B12 and its presence in just a few natural food varieties cause some impacts in the appropriate human consumption of vitamin B12 and its absence in our metabolism affects the vital red blood cells production and several activities of the neurological system. The purpose of this project will be to produce microcapsules containing vitamin B12 by co-extrusion technique using a high-speed video camera and determine the controlling parameters of the process. In addition, capsules will be evaluated in terms of efficiency, stability during storage and the release of vitamin B12 in simulated gastro-intestinal conditions. Besides of characterizing those microparticles according to the morphology and size. (AU)

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