Advanced search
Start date
Betweenand

Neuroendocrine control of hydromineral balance in obese rats

Grant number: 16/20132-7
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: November 01, 2016
End date: October 31, 2017
Field of knowledge:Biological Sciences - Physiology - Physiology of Organs and Systems
Principal Investigator:José Antunes Rodrigues
Grantee:Gabriel de Andrade Ishioka
Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:13/09799-1 - Energy balance and body fluid homeostasis control: from cells to the physiological systems, AP.TEM

Abstract

Obesity is a well-studied phenomenon concerning its nutritional, metabolic, and cardiovascular aspects. This is due to its elevated prevalence around the world. It is generally associated with a variety of comorbidities such as cardiovascular diseases, diabetes, hypertension, and dyslipidemia. However, little is known about how the systems that regulate hydroelectrolytic homeostasis are acting in an obese individual. This work has the objective to clarify how obesity modulates the hydromineral balance. For this purpose, Wistar male rats treated with a high-fat diet (60% lipids) during 15 weeks will be submitted to a 24-h fluid deprivation. Functional, hormonal, and gene expression parameters will be determined in these animals in order to observe the effect of adiposity on the fluid homeostasis.

News published in Agência FAPESP Newsletter about the scholarship:
More itemsLess items
Articles published in other media outlets ( ):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DOS-SANTOS, RAONI CONCEICAO; ISHIOKA, GABRIEL; COGNUCK, SUSANA QUIROS; MANTOVANI, MILENE; CALIMAN, IZABELA FACCO; KAGOHARA ELIAS, LUCILA LEICO; ANTUNES-RODRIGUES, JOSE. High-fat diet changes the behavioural and hormonal responses to water deprivation in male Wistar rats. Experimental Physiology, v. 107, n. 12, p. 13-pg., . (13/09799-1, 16/20132-7, 18/18071-5, 19/01260-2)