The effect of triclosan on clinical conditions and salivary microbiota in children from generalized aggressive periodontitis parents

• Grant number: 16/20361-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2016
• End date: November 30, 2017
• Field of knowledge: Health Sciences - Dentistry - Periodontology
• Principal Investigator: Renato Corrêa Viana Casarin
• Grantee: Henrique Tonelli
• Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil

Abstract

The generalized aggressive periodontitis (GAP) is an inflammatory disease that can cause rapid and severe destruction of the periodontal tissues. Among its main features are a relatively constant microbiological profile and familial aggregation of cases. In this regard, studies of children of individuals with GAP were performed and identified early clinical and microbiological changes in these individuals suggesting the presence of factors that favor the development of the disease. Thus, the present study aims to evaluate whether toothpastes containing Triclosan would have a benefit in controlling biofilm and alter the salivary microbiota in children whose parents have GAP when compared to children of parents with periodontal health. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MONTEIRO, MABELLE FREITAS; TONELLI, HENRIQUE; REIS, AURELIO AMORIM; CASATI, MARCIO ZAFFALON; SILVERIO, KARINA GONZALES; NOCITI JUNIOR, FRANCISCO HUMBERTO; SALLUM, ENILSON ANTONIO; CASARIN, RENATO CORREA VIANA. Triclosan toothpaste as an adjunct therapy to plaque control in children from periodontitis families: a crossover clinical trial. CLINICAL ORAL INVESTIGATIONS, v. 24, n. 4, p. 1421-1430, APR 2020. (16/20361-6)