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Production of bounded interdigitated electrodes for biosensors for detection of cancer biomarkers

Grant number: 17/12096-3
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2017
Effective date (End): February 28, 2018
Field of knowledge:Physical Sciences and Mathematics - Physics
Principal Investigator:Osvaldo Novais de Oliveira Junior
Grantee:Roberto Hiroshi Matos Furuta
Home Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
Associated research grant:13/14262-7 - Nanostructured films from biologically-relevant materials, AP.TEM


Diagnostic techniques for early cancers of different types of cancer are of great relevance, given that cancer is the third most common cause of death in developing countries. One of the strategies to identify the disease is to detect biomarkers with biosensors, such as those based on measurements of electrical impedance and capacitance. This type of biosensor allows the detection of analytes without using markers and with little treatment of the sample under analysis. This project intends to produce inexpensive printed interdigitated electrodes for capacitive biosensors used in the detection of cancer biomarkers. The electrodes will be produced with screen printing on cheap and flexible substrates, such as plastic and paper. To construct the biosensors, the electrodes will be covered with different nanomaterials aiming at the optimization of the electrical and analytical properties. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
IBANEZ-REDIN, GISELA; FURUTA, ROBERTO H. M.; WILSON, DEIVY; SHIMIZU, FLAVIO M.; MATERON, ELSA M.; REBOLHO BATISTA ARANTES, LIDIA MARIA; MELENDEZ, MATIAS E.; CARVALHO, ANDRE L.; REIS, RUI MANUEL; CHAUR, MANUEL N.; GONCALVES, DEBORA; OLIVEIRA, JR., OSVALDO N. Screen-printed interdigitated electrodes modified with nanostructured carbon nano-onion films for detecting the cancer biomarker CA19-9. Materials Science & Engineering C-Materials for Biological Applications, v. 99, p. 1502-1508, JUN 2019. Web of Science Citations: 0.

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