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Incidence of ramifications located in the apical 3 mm of the root with the use of digital periapical radiography, CBCT and computerized microtomography

Grant number: 17/05391-9
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): September 01, 2017
Effective date (End): February 29, 2020
Field of knowledge:Health Sciences - Dentistry - Endodontics
Principal Investigator:Alexandre Augusto Zaia
Grantee:Natália Siqueira Lobo
Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil
Associated scholarship(s):18/25051-0 - Sealing of ramifications located in the apical 1 mm of the root when using two different working lengths: a nanoCT evaluation, BE.EP.MS


It is recognized in the literature that the apical region of the roots presents a varied morphology and can exhibit the presence of numerous ramifications, such as apical delta, secondary and accessory canals. These ramifications may harbor a high prevalence of bacterial cells, capable of proliferating and inducing an inflammatory response, with consequent bone resorption. Thus, it is important to emphasize the role of apical ramifications in relation to contamination and failure of endodontic treatment. Therefore, the aim of this study is to evaluate the incidence of root canal ramifications in the last 3 mm of the dental root, using digital radiographic, Cone-beam Computed Tomography (CBCT) and Micro Computed Tomography (Micro-CT) and, evaluating among these methods, if there are any differences in the visual aspects of root canal ramifications in this region. This study will have a sample of 60 incisor roots, 60 canine roots, 60 premolar roots and 60 molar roots, adding up to 240 dental roots. The GE 1000® will be used to obtain the digital radiography images, the Picasso Trio for CBCT images and SkyScan 1174 for micro-CT images. All images will be evaluated by 3 specialists, two endodontists and one radiologist. Statistical analysis will be performed by using Kappa to verify the reproducibility of the described method, assessing intraobserver and interobserver agreement. The sensitivity, specificity, accuracy and the Receiver Operating Characteristic (ROC) curve will also be calculated and analyzed by ANOVA, followed by the Tukey test with a significance level of 5% (± = 0.05). It is expected that by assessing the incidence of these ramifications, the endodontist will have a better understanding of the importance that these canals have in the diagnosis, planning and treatment of endodontic problems. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
NATALIA SIQUEIRA LOBO; VICTOR AQUINO WANDERLEY; YURI NEJAIM; AMANDA FARIAS GOMES; ALEXANDRE AUGUSTO ZAIA. Assessment of Ramifications in the Apical Region of Root Canals: A Micro-CT Study in a Brazilian Population. Brazilian Dental Journal, v. 31, n. 5, p. 505-510, . (17/05391-9)
NATALIA SIQUEIRA LOBO; REINHILDE JACOBS; KARLA DE FARIA VASCONCELOS; VICTOR AQUINO WANDERLEY; BERNARDO CAMARGO DOS SANTOS; MARINA ANGÉLICA MARCIANO; ALEXANDRE AUGUSTO ZAIA. Influence of working length and anatomical complexities on the apical root canal filling: a nano-CT study. Brazilian Dental Journal, v. 33, n. 3, p. 1-7, . (18/25051-0, 17/05391-9)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
LOBO, Natália Siqueira. Assessement of root canal system apical region: an imaging study. 2020. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Faculdade de Odontologia de Piracicaba Piracicaba, SP.

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