Effectiveness of Contingency Management in the treatment of crack addiction for crack users living in the "Crackland" region. A Crossover Randomized Clinical Trial.

• Grant number: 17/05371-8
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: October 01, 2017
• End date: December 31, 2020
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal Investigator: Jair de Jesus Mari
• Grantee: André de Queiroz Constantino Miguel
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated scholarship(s): 17/22004-9 - BEPE/FAPESP international training for the project effectiveness of contingency management in the treatment of crack addiction for individuals living in the Crackland region: a crossover randomized clinical trial , BE.EP.PD

Abstract

Crack addiction has become a severe public health problem in Brasil. Crack users present higher prevalence of psychiatric comorbidities, sexual transmitted infections and unemployment with higher probability of living or have lived in the streets, higher history of incarceration and engagement in illegal activities. For the last 20 years a treatment called Contingency Management (CM) have achieved the best results regarding reduction of drug use, promotion of abstinence, treatment participation and retention. The first CM study conducted in Brazil advocates for the efficacy on all of these outcomes, suggesting that CM can be effective in a Brazilian population of crack users. The objective of this study is to evaluate the effectiveness of CM for crack users living in the "Crackland" region. To achieve that goal regular staff from Helvetia and Cratod services will be capacitated in CM to latter on apply the CM protocol. This will be a crossover randomized clinical trial composed of a sample of 200 subjects with current diagnose for crack/cocaine dependence. After 12 weeks of intervention, participants in the control condition (standard treatment alone) will receive 12 weeks of the experimental treatment (standard treatment plus CM) and participants in the experimental condition will receive 12 weeks of the control procedure. Our hypothesis is that participants will have a better response to all studied outcomes when receiving the experimental procedure.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CONSTANTINO MIGUEL, ANDRE DE QUEIROZ; MADRUGA, CLARICE SANDI; SIMOES, VIVIANE; YAMAUCHI, RODOLFO; DA SILVA, CLAUDIO JERONIMO; MCDONELL, MICHAEL; MCPHERSON, STERLING; ROLL, JOHN; LARANJEIRA, RONALDO RAMOS; MARI, JAIR DE JESUS. Contingency management is effective in promoting abstinence and retention in treatment among crack cocaine users with a previous history of poor treatment response: a crossover trial. PSICOLOGIA-REFLEXAO E CRITICA, v. 32, JUL 15 2019. (11/01469-7, 17/22004-9, 17/05371-8, 13/04138-7)

MIGUEL, ANDRE Q. C.; MADRUGA, CLARICE S.; SIMOES, VIVIANE; YAMAUCHI, RODOLFO; DA SILVA, CLAUDIO J.; ABDALLA, RENATA R.; MCDONELL, MICHAEL; MCPHERSON, STERLING; ROLL, JOHN M.; MARI, JAIR J.; et al. Crack cocaine users views regarding treatment with contingency management in Brazil. SUBSTANCE ABUSE TREATMENT PREVENTION AND POLICY, v. 13, FEB 12 2018. (11/01469-7, 17/05371-8, 13/04138-7)

ANDRÉ Q. C. MIGUEL; VIVIANE SIMÕES; RODOLFO YAMAUCHI; CLARICE S. MADRUGA; CLAUDIO J. DA SILVA; RONALDO R. LARANJEIRA; JOHN M. ROLL; CRYSTAL L. SMITH; STERLING M. MCPHERSON; JAIR J. MARI. Perfil sociodemográfico e clínico de indivíduos em busca de tratamento para o uso de crack que vivem na “Cracolândia”. Jornal Brasileiro de Psiquiatria, v. 71, n. 1, p. 50-55, 2022-02-21. (17/22004-9, 17/05371-8)