Advanced search
Start date

Analytical method employing QuEChERS and UHPLC-MS/MS for albendazole and its metabolites determination in fish fillet

Grant number: 17/26290-6
Support Opportunities:Scholarships abroad - Research Internship - Master's degree
Effective date (Start): February 01, 2018
Effective date (End): July 31, 2018
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Science
Principal Investigator:Jonas Augusto Rizzato Paschoal
Grantee:Ana Carolina Vellosa Portela
Supervisor: Mark Mooney
Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Research place: Queen's University Belfast, Northern Ireland  
Associated to the scholarship:16/16593-9 - Estimation and evaluation of withdrawal periods for albendazole and its metabolites in fish, BP.MS


The present project aims improve the scientific evolution intended into the ongoing masters' modality project granted by FAPESP through the process 2016/16593-9 entitled "Estimation and evaluation of withdrawn period of albendazole and its metabolites in fish fillets". A 6-month internship is proposed at Queen's University of Belfast (QUB), Northern Ireland. The internship will be supervised by Dr Mark Mooney, who leads research projects at the Institute for Global Food Security with focus on monitoring and detecting chemical contaminants in animal food. The present project represents an important step for the scientific partnership consolidation between the University of São Paulo (USP) and QUB which has been started through the ongoing financed granted into the FAPESP-SPRINT call (process 2014/50755-0). In this way, this project intends to increase the analytical chemistry knowledge involving food safety issues. Currently, we have developed and validated an analytical method to determine residues of albendazole (ABZ) - a broad-spectrum antiparasitic against helminthic parasites with potential to be used in aquaculture - and its metabolites in fish fillet employing fish species of Brazilian commercial importance. ABZ has been considered to be effective in aquaculture as antiparatic drug; however it is not regulated for fish farming. In order to consider it for regular use in fish farming, reliable analytical methods are demanded to determine ABZ residues in fish meat. Through this project, we intend to evaluate the transfer feasibility of the already develped method to another laboratory (QUB), using more modern equipments. It will also be evaluated to include lyophilization procedure during the sample pre-treatment step to improve the analytical performance (precision).

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Please report errors in scientific publications list using this form.