Study of cardiorespiratory interaction and the supply of peripheral and cerebral oxygen as modulators of exercise capacity during bilevel application in the coexistence of COPD-CHF

• Grant number: 18/03233-0
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: April 01, 2018
• End date: May 31, 2023
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Audrey Borghi Silva
• Grantee: Cássia da Luz Goulart
• Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated research grant: 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach, AP.TEM
• Associated scholarship(s): 20/13465-5 - Identification of prognostic variables from the cardiopulmonary exercise test to stratify Heart Failure severity, BE.EP.DD

Abstract

Study of cardiorespiratory interaction and the supply of peripheral and cerebral oxygen as modulators of exercise capacity during bilevel application in the coexistence of COPD-CHF. (AU)

Scientific publications

(32)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

C.F. FAGUNDES; L. DI THOMMAZO-LUPORINI; C.L. GOULART; D. BRAATZ; A. DITOMASO; A. BORGHI-SILVA. Reference equations of oxygen uptake for the step test in the obese population. Brazilian Journal of Medical and Biological Research, v. 55, 2022-03-21. (18/03233-0, 20/13465-5, 15/26501-1)

DA LUZ GOULART, CASSIA; TRIMER, RENATA; GARCIA-ARAUJO, ADRIANA SANCHES; CARUSO, FLAVIA ROSSI; RICCI, PAULA ANGELICA; SANTOS, POLLIANA BATISTA; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY. Validity, intra and inter-reliability of manual evaluation of the respiratory muscle strength in asthmatic patients. PHYSIOTHERAPY RESEARCH INTERNATIONAL, JUN 2020. (18/03233-0, 15/26501-1)

ARAKELIAN, V. M.; GOULART, C. L.; MENDES, R. G.; CARUSO, F. C.; BALDISSERA, V.; ARENA, R.; BORGHI-SILVA, A.. Cardiorespiratory and metabolic determinants during moderate and high resistance exercise intensities until exhaustion using dynamic leg press: comparison with critical load. Brazilian Journal of Medical and Biological Research, v. 51, n. 11, 2018. (09/01842-0, 18/03233-0)

C.L. GOULART; F.R. CARUSO; G.P.T. ARÊAS; P.B. DOS SANTOS; P.F. CAMARGO; L.C.S. DE CARVALHO; M.G. ROSCANI; R.G. MENDES; A. BORGHI-SILVA. Impact of chronic obstructive pulmonary disease on linear and nonlinear dynamics of heart rate variability in patients with heart failure. Brazilian Journal of Medical and Biological Research, v. 54, n. 2, 2020-11-27. (15/26501-1, 18/03233-0)

OLIVEIRA, MURILO REZENDE; BACK, GUILHERME DIONIR; KONZEN, VANESSA DE MELLO; GARCIA-ARAUJO, ADRIANA SANCHES; GOULART, CASSIA DA LUZ; SILVA, REBECA NUNES; WIBELINGER, LIA MARA; DIXIT, SNEHIL; ARENA, ROSS; BORGHI-SILVA, AUDREY. Noninvasive ventilation in patients with COVID-19 from the perspective of the risk of contamination: a narrative review. EXPERT REVIEW OF RESPIRATORY MEDICINE, v. 16, n. 1, DEC 2021. (18/03233-0)

BAFFA, GIOVANA SALGADO; GOULART, CASSIA DA LUZ; CARUSO, FLAVIA ROSSI; GARCIA DE ARAUJO, ADRIANA S.; DOS SANTOS, POLLIANA BATISTA; ROSCANI, MELIZA GOI; PRONE, FABIO RODRIGO; BONJORNO, JOSE CARLOS; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY. Noninvasive ventilation can modulate heart rate variability during high-intensity exercise in COPD-CHF patients. HEART & LUNG, v. 50, n. 5, p. 609-614, SEP-OCT 2021. (18/03233-0)

KAMILA MOHAMMAD KAMAL MANSOUR; CÁSSIA DA LUZ GOULART; LUIZ CARLOS SOARES DE CARVALHO-JUNIOR; RENATA TRIMER; AUDREY BORGHI-SILVA; ANDRÉA LÚCIA GONÇALVES DA SILVA. Pontos de corte da função pulmonar e capacidade funcional determinantes para sarcopenia e dinapenia em pacientes com DPOC. Jornal Brasileiro de Pneumologia, v. 45, n. 6, 2019-10-17. (15/26501-1, 18/03233-0)

GOULART, CASSIA DA LUZ; SILVA, REBECA NUNES; OLIVEIRA, MURILO REZENDE; GUIZILINI, SOLANGE; ROCCO, ISADORA SALVADOR; MENDEZ, VANESSA MARQUES FERREIRA; BONJORNO, JOSE CARLOS; CARUSO, FLAVIA ROSSI; ARENA, ROSS; BORGHI-SILVA, AUDREY. Lifestyle and rehabilitation during the COVID-19 pandemic: guidance for health professionals and support for exercise and rehabilitation programs. EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, v. 19, n. 11, p. 1385-1396, NOV 2 2021. (15/26501-1, 18/03233-0)

GOULART, CASSIA LUZ; TINOCO AREAS, GUILHERME PEIXOTO; CARUSO, FLAVIA ROSSI; GARCIA ARAUJO, ADRIANA S.; GARCIA DE MOURA, SILVIA CRISTINA; CATAI, APARECIDA MARIA; BELTRAME, THOMAS; DE CARVALHO JUNIOR, LUIZ CARLOS; DOS SANTOS, POLLIANA BATISTA; ROSCANI, MELIZA GOI; et al. Effect of high-intensity exercise on cerebral, respiratory and peripheral muscle oxygenation of HF and COPD-HF patients. HEART & LUNG, v. 50, n. 1, p. 113-120, JAN-FEB 2021. (15/26501-1, 18/03233-0)

BORGHI-SILVA, AUDREY; BACK, GUILHERME DIONIR; DE ARAUJO, ADRIANA S. GARCIA; OLIVEIRA, MURILO REZENDE; GOULART, CASSIA DA LUZ; SILVA, REBECA NUNES; BASSI, DANIELA; MENDES, RENATA GONCALVES; ARENA, ROSS. COVID-19 seen from a syndemic perspective: Impact of unhealthy habits and future perspectives to combat these negative interactions in Latin America. PROGRESS IN CARDIOVASCULAR DISEASES, v. 71, p. 7-pg., 2022-03-01. (18/03233-0, 15/26501-1)

GOULART, C. L.; OLIVEIRA, M. R.; RENATA, M. G.; SILVA, A. B.. Prognostic Value of Key Variables from Cardiopulmonary Exercise Testing in Patients with COPD: 42-Month Follow-Up. American Journal of Respiratory and Critical Care Medicine, v. 205, p. 1-pg., 2022-05-01. (18/03233-0, 15/26501-1, 20/13465-5)

BORGHI-SILVA, AUDREY; GARCIA-ARAUJO, ADRIANA S.; WINKERMANN, ELIANE; CARUSO, FLAVIA R.; BASSI-DIBAI, DANIELA; GOULART, CASSIA DA LUZ; DIXIT, SNEHIL; BACK, GUILHERME DIONIR; MENDES, RENATA G.. Exercise-Based Rehabilitation Delivery Models in Comorbid Chronic Pulmonary Disease and Chronic Heart Failure. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 8, p. 9-pg., 2021-10-13. (18/03233-0, 15/26501-1)

DA LUZ GOULART, CASSIA; TRIMER, RENATA; GARCIA-ARAUJO, ADRIANA SANCHES; CARUSO, FLAVIA ROSSI; RICCI, PAULA ANGELICA; SANTOS, POLLIANA BATISTA; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY. Validity, intra and inter-reliability of manual evaluation of the respiratory muscle strength in asthmatic patients. PHYSIOTHERAPY RESEARCH INTERNATIONAL, v. 25, n. 4, p. 8-pg., 2020-06-09. (18/03233-0, 15/26501-1)

GOULART, SSIA DA LUZ; CARUSO, FLAVIA ROSSI; DE ARAUJO, ADRIANA S. GARCIA; CRISTINA GARCIA DE MOURA, SILVIA; CATAI, APARECIDA MARIA; BATISTA DOS SANTOS, POLLIANA; KABBACH, ERIKA Z.; ARENA, ROSS; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY. The Effect of Adding Noninvasive Ventilation to High-Intensity Exercise on Peripheral and Respiratory Muscle Oxygenation. Respiratory Care, v. 68, n. 3, p. 10-pg., 2023-03-01. (18/03233-0)

RIZZATTI, F. P.; FARIA, R. A.; GOULART, C. L.; MARINHO, R. S.; FIRMINO, S. M.; MENDES, R. G.; BORGHI, A.; ROSCANI, M. G.. Right Ventricle Diastolic Diameter Can Be Used as a Predictor of Adverse Outcomes in COPD Patients. American Journal of Respiratory and Critical Care Medicine, v. 207, p. 1-pg., 2023-05-01. (18/03233-0)

GOULART, C.; SCHWARTZMANN, P. V.; AEREAS, G. P. T.; DOS SANTOS, P. B.; MARINHO, R. S.; MANSOUR, K. M. K.; MENDES, R. G.; DA SILVA, A. L. G.; CARUSO, F. R.; BORGHI-SILVA, A.. Clinical Variables of Cardiopulmonary Exercise Testing: Identifying Relative Cut-Off Scores to Determine Prognostic Values in Chagas-Heart Failure Patients. American Journal of Respiratory and Critical Care Medicine, v. 199, p. 2-pg., 2019-01-01. (18/03233-0, 15/26501-1)

GOULART, CASSIA DA LUZ; CARUSO, FLAVIA ROSSI; DE ARAUJO, ADRIANA SANCHES GARCIA; MOURA, SILVIA CRISTINA GARCIA DE; CATAI, APARECIDA MARIA; AGOSTONI, PIERGIUSEPPE; MENDES, RENATA GONCALVES; ARENA, ROSS; BORGHI-SILVA, AUDREY. an Non-invasive Ventilation Modulate Cerebral, Respiratory, and Peripheral Muscle Oxygenation During High-Intensity Exercise in Patients With COPD-HF. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 8, JAN 31 2022. (20/13465-5, 18/03233-0)

OLIVEIRA, MURILO REZENDE; BACK, GUILHERME DIONIR; GOULART, CASSIA DA LUZ; DOMINGOS, BIANCA CRISTINA; ARENA, ROSS; BORGHI-SILVA, AUDREY. Endothelial function provides early prognostic information in patients with COVID-19: A cohort study. RESPIRATORY MEDICINE, v. 185, AUG-SEP 2021. (15/26501-1, 18/03233-0)

BORGHI-SILVA, AUDREY; GOULART, CASSIA DA LUZ; CARRASCOSA, CLAUDIA R.; OLIVEIRA, CRISTINO CARNEIRO; BERTON, DANILO C.; DE ALMEIDA, DIRCEU RODRIGUES; NERY, LUIZ EDUARDO; ARENA, ROSS; NEDER, J. ALBERTO. Proportional Assist Ventilation Improves Leg Muscle Reoxygenation After Exercise in Heart Failure With Reduced Ejection Fraction. FRONTIERS IN PHYSIOLOGY, v. 12, JUN 21 2021. (15/26501-1, 18/03233-0)

GOULART, CASSIA DA LUZ; CARUSO, FLAVIA ROSSI; DE ARAUJO, ADRIANA S. GARCIA; TINOCO ARE, GUILHERME PEIXOTO; GARCIA DE MOURA, SILVIA CRISTINA; CATAI, APARECIDA MARIA; MENDES, RENATA GONCALVES; PHILLIPS, SHANE A.; ARENA, ROSS; GONCALVES DA SILVA, ANDREA LUCIA; et al. Non-invasive ventilation improves exercise tolerance and peripheral vascular function after high-intensity exercise in COPD-HF patients. RESPIRATORY MEDICINE, v. 173, NOV 2020. (18/03233-0)

GOULART, C.; AGOSTONI, P.; SALVIONI, E.; SILVA, R. N.; KAMINSKY, L. A.; MYERS, J.; ARENA, R.; MENDES, R. GONCALVES; BORGHI-SILVA, A.; MENDES, R.. Exercise Oscillatory Breathing in Heart Failure: clinical and prognostic implications. European Respiratory Journal, v. 60, p. 2-pg., 2022-09-04. (18/03233-0, 15/26501-1)

GOULART, CASSIA DA LUZ; AGOSTONI, PIERGIUSEPPE; SALVIONI, ELISABETTA; KAMINSKY, LEONARD A.; MYERS, JON; ARENA, ROSS; BORGHI-SILVA, AUDREY. Exercise oscillatory breathing in heart failure with reduced ejection fraction: clinical implication. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, v. N/A, p. 7-pg., 2022-06-16. (20/13465-5, 18/03233-0)

GOULART, CASSIA LUZ; DOS SANTOS, POLLIANA BATISTA; CARUSO, FLAVIA ROSSI; TINOCO AREAS, GUILHERME PEIXOTO; MARINHO, RENAN SHIDA; CAMARGO, PATRICIA DE FARIA; ALEXANDRE, TIAGO SILVA; OLIVEIRA, CLAUDIO R.; GONCALVES DA SILVA, ANDREA LUCIA; MENDES, RENATA GONCALVES; et al. The Value of Cardiopulmonary Exercise Testing in Determining Severity in Patients with both Systolic Heart Failure and COPD. SCIENTIFIC REPORTS, v. 10, n. 1, MAR 9 2020. (18/03233-0, 15/26501-1)

FAGUNDES, C. F.; DI THOMMAZO-LUPORINI, L.; GOULART, C. L.; BRAATZ, D.; DITOMASO, A.; BORGHI-SILVA, A.. Reference equations of oxygen uptake for the step test in the obese population. Brazilian Journal of Medical and Biological Research, v. 55, n. 1, p. 8-pg., 2022-01-01. (18/03233-0, 15/26501-1, 20/13465-5)

FARIA, RICARDO ALEXANDRE; GOULART, CASSIA DA LUZ; DOS SANTOS, POLLIANA B.; MARINHO, RENAN SHIDA; FIRMINO, STELLA MARIS; RIZZATTI, FABIOLA P. G.; MENDES, RENATA G.; BORGHI-SILVA, AUDREY; ROSCANI, MELIZA GOI. Right ventricle diastolic diameter as a predictor of adverse outcome of patients with chronic pulmonary obstructive disease: One-year follow-up. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, v. 365, n. 2, p. 3-pg., 2023-02-01. (18/03233-0)

FARIA, R. A.; GOULART, C. L.; SANTOS, P. B.; MARINHO, R. S.; FIRMINO, S. M.; RIZZATTI, F. P. G.; MENDES, R. G.; BORGHI-SILVA, A.; ROSCANI, M. G.. Association of right ventricle diastolic diameter with pulmonary function, exercise tolerance and exacerbation period in patients with chronic obstructive pulmonary disease: A prospective study. HEART & LUNG, v. 55, p. 5-pg., 2022-09-01. (18/03233-0)

BACK, G.; DA LUZ GOULART, C.; OLIVEIRA, M.; CAMARGO, P. F.; OLIVEIRA, C.; WENDE, K.; BONJORNO JUNIOR, J.; ARBEX, R.; CARUSO, F.; ARENA, R.; et al. Does Mild to Moderate COVID-19 Infection Impair Lung Function and Exercise Capacity After One Month of Recovery?. American Journal of Respiratory and Critical Care Medicine, v. 205, p. 1-pg., 2022-05-01. (18/03233-0, 20/13465-5)

SIMOES, RODRIGO POLAQUINI; GOULART, CASSIA DA LUZ; CARUSO, FLAVIA ROSSI; ARAUJO, ADRIANA S. GARCIA DE; DE MOURA, SILVIA CRISTINA GARCIA; CATAI, APARECIDA MARIA; DOS SANTOS, POLLIANA BATISTA; CAMARGO, PATRICIA DE FARIA; MARINHO, RENAN SHIDA; MENDES, RENATA GONCALVES; et al. Non-invasive ventilatory support accelerates the oxygen uptake and heart rate kinetics and improves muscle oxygenation dynamics in COPD-HF patients. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, v. 366, n. 2, p. 11-pg., 2023-08-01. (18/03233-0, 20/13465-5)

GOULART, CASSIA; CARUSO, FLAVIA; ARAUJO, ADRIANA; SANTOS, POLLIANA; AREAS, GUILHERME; CASALE, GUILHERME; MENDES, RENATA; DA SILVA, ANDREA; BORGHI-SILVA, AUDREY. Non-invasive ventilation can modulate the responses of vascular reactivity in COPD-HF patients to high-intensity exercise. European Respiratory Journal, v. 56, p. 3-pg., 2020-09-07. (18/03233-0, 15/26501-1)

CARUSO, FLAVIA ROSSI; GOULART, CASSIA LUZ; BONJORNO, JOSE CARLOS, JR.; SANCHES ARAUJO, ADRIANA GARCIA; MENDES, RENATA GONCALVES; BORGHI-SILVA, AUDREY. Effect of high-intensity exercise on respiratory and peripheral muscle oxygenation in HF and COPD-HF patients. European Respiratory Journal, v. 56, p. 2-pg., 2020-09-07. (18/03233-0, 15/26501-1, 18/18133-0)

GOULART, CASSIA DA LUZ; SILVA, REBECA NUNES; AGOSTONI, PIERGIUSEPPE; FRANSSEN, FRITS M. E.; MYERS, JONATHAN; ARENA, ROSS; BORGHI-SILVA, AUDREY. Exercise oscillatory ventilation in patients with coexisting chronic obstructive pulmonary disease and heart failure: Clinical implications. RESPIRATORY MEDICINE, v. 217, p. 5-pg., 2023-10-01. (18/03233-0, 20/13465-5)

GOULART, CASSIA DA LUZ; OLIVEIRA, MURILO REZENDE; ALBURQUERQUE SENDIN, FRANCISCO; MENDES, RENATA GONCALVES; ARENA, ROSS; BORGHI-SILVA, AUDREY. Prognostic value of key variables from cardiopulmonary exercise testing in patients with COPD: 42-month follow-up. RESPIRATORY MEDICINE, v. 197, p. 6-pg., 2022-04-20. (18/03233-0, 20/13465-5)