Organic reaction at single molecule level: synthesis of a fluorescent imidazole

• Grant number: 18/17660-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): February 01, 2019
• Effective date (End): January 31, 2020
• Field of knowledge: Physical Sciences and Mathematics - Chemistry
• Principal Investigator: Marcelo Henrique Gehlen
• Grantee: Larissa Schumekel Foltran
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil

Abstract

In this research project, advanced fluorescence microscopy techniques will be applied to investigate the amino-catalysis reactions at single-molecule (SM) level forming fluorescent imidazole derivatives. Such compounds will provide intramolecular charge transfer (ICT) state due to the presence of electron withdrawing groups such as CN. These compounds may found applications in OLED with TADF effect. The development of such research topic of reactivity at SM level allows further optimization of catalysts and provides a completely new approach in chemical kinetics and photochemistry.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GEHLEN, MARCELO H.; FOLTRAN, LARISSA S.; KIENLE, DANIEL F.; SCHWARTZ, DANIEL K.. Single-Molecule Observations Provide Mechanistic Insights into Bimolecular Knoevenagel Amino Catalysis. Journal of Physical Chemistry Letters, v. 11, n. 22, p. 9714-9724, NOV 19 2020. (18/17660-7, 18/22159-5)