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Ultra-processed foods and 'protein leverage hypothesis': a study in seven countries

Grant number: 18/17972-9
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): January 01, 2019
Effective date (End): December 31, 2021
Field of knowledge:Health Sciences - Nutrition - Nutritional Analysis of Population
Principal researcher:Carlos Augusto Monteiro
Grantee:Eurídice Martínez Steele
Home Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:15/14900-9 - Consumption of ultra-processed foods, dietary nutrient profile diet and obesity in seven countries, AP.TEM


In 2005, Simpson and Raubenheimer, based on experimental studies, postulated that human diets with insufficient protein content would lead to excessive calorie consumption (Protein Leverage Hypothesis - PLH), mainly due to a physiological priority to mantain protein intake constant. In this way, factors leading to a reduction in the protein content of contemporary diets could lead to an increase in calorie consumption and thus explain at least in part the worldwide epidemic of obesity. One of these factors, according to these authors, may be the tendency observed in several countries of substituting minimally processed foods by ultra-processed foods. In her doctoral dissertation, analyzing population data from national research on food consumption in the US, the candidate found evidence supporting PLH and the role of ultra-processed foods in increasing calorie consumption (Martinez Steele et al 2017). In this project, carried out in collaboration with Simpson and Raubenheimer, she will extend this study to include six other countries (Brazil, Colombia, Chile, Canada, the United Kingdom and Australia), always using national data on food consumption as data sources. This project is part of the NUPENS/USP thematic project studying the effects of ultra-processed food consumption on diet quality and human health in seven countries. (AU)

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Scientific publications (13)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
STEELE, EURIDICE MARTINEZ; BATIS, CAROLINA; CEDIEL, GUSTAVO; LOUZADA, MARIA LAURA DA COSTA; KHANDPUR, NEHA; MACHADO, PRISCILA; MOUBARAC, JEAN-CLAUDE; RAUBER, FERNANDA; JEDLICKI, MARCELA REYES; LEVY, RENATA BERTAZZI; et al. he burden of excessive saturated fatty acid intake attributed to ultra-processed food consumption: a study conducted with nationally representative cross-sectional studies from eight countrie. JOURNAL OF NUTRITIONAL SCIENCE, v. 10, . (16/14302-7, 18/17972-9, 15/14900-9)
BARALDI, LARISSA GALASTRI; STEELE, EURIDICE MARTINEZ; LOUZADA, MARIA LAURA C.; MONTEIRO, CARLOS A.. Associations between ultraprocessed food consumption and total water intake in the US population. JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS, v. 121, n. 9, p. 1695-1703, . (18/17972-9, 15/14900-9)
LAZZERI, BRUNA; LEOTTI, VANESSA BIELEFELDT; SOLDATELI, BETINA; GIUGLIANI, ELSA REGINA; MONTEIRO, CARLOS AUGUSTO; MARTINEZ STEELE, EURIDICE; PEDROTTI, LUANA GIONGO; DREHMER, MICHELE. Effect of a healthy eating intervention in the first months of life on ultraprocessed food consumption at the age of 4-7 years: a randomised clinical trial with adolescent mothers and their infants. BRITISH JOURNAL OF NUTRITION, v. 126, n. 7, p. 1048-1055, . (18/17972-9)
JUUL, FILIPPA; PAREKH, NIYATI; MARTINEZ-STEELE, EURIDICE; MONTEIRO, CARLOS AUGUSTO; CHANG, VIRGINIA W.. ltra-processed food consumption among US adults from 2001 to 201. AMERICAN JOURNAL OF CLINICAL NUTRITION, v. 115, n. 1, p. 211-221, . (18/17972-9)
NERI, DANIELA; STEELE, EURIDICE MARTINEZ; KHANDPUR, NEHA; CEDIEL, GUSTAVO; ZAPATA, MARIA ELISA; RAUBER, FERNANDA; MARRON-PONCE, JOAQUIN A.; MACHADO, PRISCILA; DA COSTA LOUZADA, MARIA LAURA; ANDRADE, GIOVANNA CALIXTO; et al. ltraprocessed food consumption and dietary nutrient profiles associated with obesity: A multicountry study of children and adolescent. Obesity Reviews, v. 23, n. 1, SI, . (15/14900-9, 18/17972-9, 16/14302-7, 16/25853-4)
STEELE, EURIDICE MARTINEZ; JUUL, FILIPPA; NERI, DANIELA; RAUBER, FERNANDA; MONTEIRO, CARLOS A.. Dietary share of ultra-processed foods and metabolic syndrome in the US adult population. PREVENTIVE MEDICINE, v. 125, p. 40-48, . (16/14302-7, 18/17972-9, 16/25853-4, 15/14900-9)
NERI, DANIELA; MARTINEZ-STEELE, EURIDICE; MONTEIRO, CARLOS AUGUSTO; LEVY, RENATA BERTAZZI. Consumption of ultra-processed foods and its association with added sugar content in the diets of US children, NHANES 2009-2014. PEDIATRIC OBESITY, v. 14, n. 12, . (18/17972-9, 16/25853-4, 15/14900-9)
LIU, JUNXIU; STEELE, EURIDICE MARTINEZ; LI, YAN; KARAGEORGOU, DIMITRA; MICHA, RENATA; MONTEIRO, CARLOS A.; MOZAFFARIAN, DARIUSH. Consumption of Ultraprocessed Foods and Diet Quality Among US Children and Adult. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, v. 62, n. 2, p. 252-264, . (18/17972-9, 15/14900-9)
STEELE, EURIDICE MARTINEZ; KHANDPUR, NEHA; SUN, QI; MONTEIRO, CARLOS A.. The impact of acculturation to the US environment on the dietary share of ultra-processed foods among US adults. PREVENTIVE MEDICINE, v. 141, . (15/14900-9, 19/22278-7, 18/17972-9)
BIDINOTTO, AUGUSTO BACELO; MARTINEZ-STEELE, EURIDICE; THOMSON, WILLIAM MURRAY; HUGO, FERNANDO NEVES; HILGERT, JULIANA BALBINOT. Investigation of direct and indirect association of ultra-processed food intake and periodontitis. Journal of Periodontology, . (18/17972-9)
YANG, QUANHE; ZHANG, ZEFENG; STEELE, EURIDICE MARTINEZ; MOORE, V, LATETIA; JACKSON, SANDRA L.. Ultra-Processed Foods and Excess Heart Age Among US Adults. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, v. 59, n. 5, p. E197-E206, . (18/17972-9)
KHANDPUR, NEHA; ROSSATO, SINARA; DROUIN-CHARTIER, JEAN-PHILIPPE; DU, MENGXI; MARTINEZ, EURIDICE; SAMPSON, LAURA; MONTEIRO, CARLOS; ZHANG, FANG FANG; WILLETT, WALTER; FUNG, TERESA T.; et al. Categorising ultra-processed foods in large-scale cohort studies: evidence from the Nurses' Health Studies, the Health Professionals Follow-up Study, and the Growing Up Today Study. JOURNAL OF NUTRITIONAL SCIENCE, v. 10, . (19/22278-7, 18/17972-9)

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