Synthesis of magnetic nanoparticles modified with MIP towards identification of the main metabolite of the herbicide diuron, the 3,4-dichloroaniline

• Grant number: 21/01587-1
• Support type: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): May 01, 2021
• Effective date (End): July 31, 2022
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal researcher: Maria Del Pilar Taboada Sotomayor
• Grantee: Larissa Prospero Santos
• Home Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

Ways of productions for obtaining food were a challenge in past centuries, and nowadays it is necessary to develop techniques to meet world demand. Among these measures, the pesticides have been used to control pests in plantations, such as herbicides, which are high use in Brazilian agriculture. However, it is known that these products are potential for the development of diseases to humans. Furthermore, these products contaminate the soil and rivers, and contributes to the reduction of animal and plant species. Therefore, it is essential to analyze these compounds for control, before the situation becomes drastic. For the identification and quantification of these products in water, was chosen the metabolite 3,4-dicloroaniline, that composes the herbicide Diuron, with the objective of evaluating its residues, and ascertaining whether the water is in healthy conditions. For this, materials will be developed, based on molecularly printed polymers, or MIPs (Molecularly Imprinted Polymers), which will be immobilized on magnetic nanoparticles. MIPs, also called biomimetic polymers, have a selector cavity, which by affinity interacts with the analyte of interest, for which it was previously synthesized. Finally, its efficiency and selectivity will be analyzed by means of High-Performance Liquid Chromatography (HPLC) for later application in analysis of rivers' samples.