In situ demineralization of enamel in response to a dentifrice with low fluoride content supplemented with phosphate

• Grant number: 07/07632-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: February 01, 2008
• End date: January 31, 2009
• Field of knowledge: Health Sciences - Dentistry - Pediatric Dentistry
• Principal Investigator: Alberto Carlos Botazzo Delbem
• Grantee: Luciene Pereira de Castro
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

The use of dentifrices with low fluoride (F) content have been a form to decrease the fluoride ingeston and, also, the dental fluorosis decrease. The aim of this study will be evaluated, in situ, wheather the dentifrice with low fluoride content supplemented with phosphate has the same efficacy of stardard dentifrice (1100 µgF/g). This study will be performed in 3 phases during 14 days and a interval of 7 days between the phases. 10 adult volunteers will use acrylic palatal appliances each containing four bovine enamel blocks. The enamel blocks will be polish and selected through surface microhardness (SMH). The volunteers will drip on the enamel blocks a solution of 20% sucrose and perform the treatment with dentifrices containing 500µgF/g and 1% of a phosphate salt, placebo (without F e P) and Crest® (1100µgF/g). After each phase, the percentage change of microhardness will be calculated (%SMH). (AU)