Evaluation of the anti-erosive effect of solutions containing sodium fluoride, tin chloride and some film-forming copolymers

Author(s)

Sávio José Cardoso Bezerra

• Document type: Master's Dissertation
• Press: São Paulo.
• Institution: Universidade de São Paulo (USP). Faculdade de Odontologia (FO/SDO)
• Defense date: 2016-11-01

Examining board members

Taís Scaramucci Forlin; Alessandra Buhler Borges; Daniela Prócida Raggio; Patricia Moreira de Freitas Costa e Silva

• Advisor: Taís Scaramucci Forlin

Abstract

Erosive tooth wear is a process that results in the loss of dental hard tissues, caused by non-bacterial acids. The association between film-forming agents with fluoride products can be a promising strategy to prevent erosion. The aim of this study is to evaluate the anti-erosive effect of solutions containing sodium fluoride (225 ppm F-), stannous chloride (800 ppm Sn2+), film-forming copolymers (Gantrez, PGA, Plasdone and CMC), and combinations thereof. Deionized water was used as a negative control. The solutions were tested in an erosion-remineralization cycling model, using enamel and dentin specimens obtained from bovine incisors (n=10 for each substrate). Cycling consisted of 2 h immersion in human saliva to allow the formation of the salivary acquired pellicle, immersion in 0.3% citric acid solution (pH = 2.6) for 5 min, followed by 120 min of exposure to clarified human saliva. This procedure was repeated 4 times a day, for 5 days. Treatment with test solutions was carried out 2 times a day, 60 min after the first and last erosive challenges, for 2 min. Surface loss (SL, in ?m) was evaluated with an optical profilometer, and data were submitted to 2-way Anova and Tukey tests (? = 0.05). In enamel, all copolymers alone showed lower SL than water, except for PGA. All solutions containing F presented less SL in relation to the control. PGA was the only copolymer capable of improving the protective effect of F. None of the copolymers was able to increase the protection of F + Sn. For dentin, only Gantrez significantly reduced SL when compared to the water. Although all solutions containing F demonstrated less SL compared to control, no copolymer was able to enhance the effect of the solutions containing F or F+Sn. (AU)

• FAPESP's process: 15/11402-8 - Evaluation of the anti-erosive effect of solutions containing sodium fluoride, tin chloride and some film-forming copolymers
• Grantee: Sávio José Cardoso Bezerra
• Support Opportunities: Scholarships in Brazil - Master