B.A. in Psychology, Faculdade de Filosofia, Ciências e Letras - Universidade de São Paulo (1960), Master's (1964) and Ph.D.(1968) in Experimental Psychology from Graduate Faculties, Columbia University, New York, NY . Has experience in Neuroscience and Experimental Psychology, focusing on Neurology, Electrophysiology and Behavior, acting on the following subjects: color vision, retina, psychophysics and electrophysiology in human subjects and animal models. (Source: Lattes Curriculum)
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The full functioning of the visual system may be threatened by various pathological conditions - genetic, environmental, infectious, neurological, metabolic - throughout life, in childhood, or in aging. Instruments to evaluate this functioning in humans may be behavioral or electrophysiological. A characteristic of these instruments is that they are non-invasive and, based on information …
Zika virus (ZIKV) is an emerging virus in Brazil, which can lead to the development of a rash illness, often associated with low-grade fever, fatigue, myalgia and conjunctivitis. The ZIKV is also related to severe neurological complications such as Guillain-Barré syndrome, and fetal abnormalities such as microcephaly. However, the crucial risk factors to the development of these severe ma…
Morphological studies of the vertebrate retina allow assessing a number of aspects of the visual capabilities in normal and abnormal physiological states. By being physically isolated from the rest of the central nervous system, the retina allows analyzing how different species perceive their environment, and how the visual information is filtered and processed by the brain. The technique…
Proposal: DMD gene products - Dp 427, Dp260, Dp140, Dp116 and DP71 - are expressed in neural tissues. Two decades ago it was found that mutations in the DMD gene leads to functional alterations in the human visual system. However it is still not completely known what type of mutations are responsible for these changes in the retinal function of patients with Duchenne and Becker muscular d…
The assessment of human visual functions is accomplished today with non-invasive psychophysical and electrophysiological methods, made available by recent computational advances which help the display of visual stimuli, the experimental programming, online data analysis, etc. In order to understand the mechanisms responsible for visual losses, still not well understood, human studies usin…
This Visiting Researcher Support application is for the visit of Dr. Balázs Vince Nagy from the Budapest University of Technology and Economics. Dr. Nagy has carried out his PhD research in mechanical engineering investigating human color discrimination and identification. During his work in Hungary Dr. Nagy coordinated 8 university subjects in various courses, supervised 13 scientific in…
(Only some records are available in English at this moment)
Snakes have high ecophysiological diversity, with different circadian rhythms and the use of different habitats, which is reflected in important variations in retinal structures. The retina is organized into layers of cells and nerve plexuses that process visual information. The types and organization of retinal neurons vary between species. In snakes, some studies have described photorec…
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease resulting from mutations or deletions in the DMD gene. It affects the expression of dystrophin proteins (Dps) leading to severe muscle impairment. The Dps are also required for the proper functioning of the central nervous system (CNS). The retina and the brain cells express at least four types of Dps. Previous studies showe…
The Alzheimer's Disease (AD) is the main cause of dementia around the world, in an ever growing older population. Most diagnostic exams are expensive and invasive, only detecting AD in the later stages of the disease. With that in mind, the pre-mortem diagnostic is one of the main focus of study of the AD, especially in its early stages, permiting that the patient has access to treatments…
(Only some records are available in English at this moment)
Color vision plays a very important role in the survival and development of primates. The ability to visually discriminate the target from a background solely by the difference in hue may be the differential for both the search for food and for the escape of predators. In old-world primates, including humans, we observe the presence of three types of cones in the retina and a trichromatic…
The group of snakes presents numerous ecological adaptations and great morphological diversity. Studies of the types of photoreceptors present in the retina of snakes, their topographic density and functional physiology are important for the understanding of behavioral patterns, ecological and adaptive aspects of the species, which differ according to their visual needs and their habitat.…
The snake group had great evolutionary success and the different species present morphological and physiological adaptations associated to the environment in which they live.The Viperidae snakes Bothrops jararaca and Crotalus durissus occupy predominantly the Atlantic forest and the cerrado biomes, respectively. Unlike C. durissus, the B. jararaca snake presents ontogenetic variations in …
(Only some records are available in English at this moment)
The visual system of snakes has phylogenetic and ecological variations related to their habits and activity patterns. Nocturnal species have typical duplex retinas, with rods and cones, while diurnal species have pure cone retinas, with no rod-like photoreceptors. Three opsin genes are expressed in retinas of most species, the rhodopsin gene RH1 expressed in rods and the cone opsin genes …
Electroretinography (ERG) is a non-invasive procedure which allows recording of electrical activity of the retina. It has been used to evaluate the different cellular circuits involved in visual processing at the retinal level, and has been used to elucidate the pathophysiological mechanisms in glaucoma disease. The aim of this proposal is to use ERG-based techniques to evaluate (1) the e…
The current study intends to evaluate several manifestations of anxiety in children and adolescents with Autistic Spectrum Disorder, such as physiological and biological measures, cognitive and behavioral symptoms and sleep and activity patterns. Four groups will be tested: two experimental groups of children with ASD with and without anxiety and two control groups of typically developing…
| 3 / 3 | Ongoing research grants |
| 45 / 25 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 51 / 21 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 106 / 56 | All research grants and scholarships |
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