CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at NUTRIÇÃO from Universidade Estadual Paulista Júlio de Mesquita Filho (2004) and master's at Clinical Medicine from Universidade Estadual Paulista Júlio de Mesquita Filho (2007). Has experience in Nutrition, focusing on Nutritional Biochemistry, acting on the following subjects: estresse oxidativo, antioxidantes, serum lipids, oxidative stress and rat. (Source: Lattes Curriculum)
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The skin is an immunologically organ where unregulated immune reactions can cause chronic inflammatory diseases such as psoriasis that affects thousands of people worldwide; It has a relapsing-remitting character and may be accompanied by diseases such as obesity, diabetes, dyslipidemia and depression. Activation of dendritic cells plays a central role in the induction and maintenance of …
The proposed project will bring together investigators from the University of Campinas (UNICAMP), and the Imperial College London (ICL) with related scientific interest. A two-year planning grant is proposed to build upon experiments as well as analysis of data combining lipidomic and functional approaches of current FAPESP projects (2018/11037-6 and 2019/06762-6). The aim of this project…
Feridas de dificil cicatrizac'ao sao uma complicac'ao comum do envelhecimento,diabetes e obesidade e existe uma forte relac'ao entre desnutric'ao, ma cicatrizac'ao einfecc'ao. Os acidos graxos omega-3 sao derivados do oleo de peixe e seu consumoesta associado a melhora das respostas imunologicas, uma vez que ativam celulas dosistema imune inato chamadas macrofagos. Macrofagos orquestram a…
Flow cytometry is a widely used technology and enshrined in various areas of research. In addition to classical tests of cell labeling, which lets us know which cell types are present in the sample, currently, this technique allows for several other tests as intracellular quantification, such as CBA ( Cytometric Beads Array ) and intracellular signaling pathways . These new possibilities …
In the evolutionary process, the ability to repair damage has become essential for organisms survival. The skin is a protective barrier constantly renewed. If this barrier is breached by an injury or infection, a rapid repair program is activated. This program is known as healing or tissue repair, consists of three interdependent and concurrent phases: the early inflammatory phase (lastin…
The skin is an immunologically organ where unregulated immune reactions can cause chronic inflammatory diseases such as Psoriasis that affects thousands of people worldwide; It has a relapsing-remitting character and may be accompanied by diseases such as Obesity, Diabetes, Dyslipidemia and depression. Activation of dendritic cells plays a central role in the induction and maintenance of …
Delay in wound healing affects millions of people worldwide, especially Diabetic individuals. It has been shown in the literature, both in laboratory animal studies and clinical trials, that oral administration of linoleic fatty acid (LA) improves different stages of tissue repair under normal conditions. Thus, in the present work, we intend to investigate the effects of oral supplementat…
Wound healing is a process that is evolutionarily conserved and essential to the survival of the species. In order to close the wound and repair the tissue, the depends on the appropriate and coordinated action of the phases: inflammatory, formation of fabric and remodeling. Thus, immunomodulatory compounds have been studied in order to accelerate wound closure or minimize tissue damage. …
Wound healing is a process characterized in three sequential and overlapping phases, which involve: inflammation, proliferation and maturation. The inflammatory response is determinant for the onset of the subsequent phase, in which the extracellular matrix (ECM) will be produced. The MEC is a three-dimensional structure that provides support, resistance, tension and organization to the t…
The skin is the first immunological barrier against physical, chemical or biological agents from the external environment and thus, must be repaired quickly when damaged. However, the delay in wound healing affects millions of people worldwide increasing susceptibility to infections, amputations and death, especially in diabetic individuals. Studies conducted by our group have demonstrate…
(Only some records are available in English at this moment)
Delayed wound healing is a common complication of cancer and diabetes, increasing infections, amputations and death. Tissue repair requires the migration of cells into the wounded region and the proliferation of new cells to restore the original density of the tissue. In this process the shift between proinflammatory molecules to proresolution is essential to limit the damage of tissue an…
Inflammation is a very important response triggered by tissue injury and its control is crucial for the reestablishment of tissue homeostasis. Nowadays, it is known that the central nervous system (CNS) can regulate the inflammatory response thought the activation of the anti-inflammatory cholinergic pathway. This mechanism involves the liberation of acetylcholine (ACH) that will bind to …
| 2 / 2 | Ongoing research grants |
| 5 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 12 / 10 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 23 / 19 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 8 |
| Citations | 101 |
| Cit./Article | 12.6 |
| Data from Web of Science | |
BURGER, BEATRIZ; KUHL, CAROLINA M. C.; CANDREVA, THAMIRIS; CARDOSO, RENATO DA S.; SILVA, JESSICA R.; CASTELUCCI, BIANCA G.; CONSONNI, SILVIO R.; FISK, HELENA L.; CALDER, PHILIP C.; VINOLO, MARCO AURELIO R.; et al. Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice. SCIENTIFIC REPORTS, v. 9, JUN 24 2019. Web of Science Citations: 1. (14/15127-9, 13/06810-4, 18/11037-6)
ANTUNES, KRIST HELEN; FACHI, JOSE LUIS; DE PAULA, ROSEMEIRE; DA SILVA, EMANUELLE FRAGA; PRAL, LAIS PASSARIELLO; DOS SANTOS, ADARA AUREA; MALAQUIAS DIAS, GREICY BRISA; VARGAS, JOSE EDUARDO; PUGA, RENATO; MAYER, FABIANA QUOOS; et al. Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response. NATURE COMMUNICATIONS, v. 10, JUL 22 2019. Web of Science Citations: 1. (12/10653-9, 13/06810-4, 17/06577-9)
FACHI, JOSE LUIS; FELIPE, JAQUELINE DE SOUZA; PRAL, LAIS PASSARIELLO; DA SILVA, BRUNA KARADI; CORREA, RENAN OLIVEIRA; PEREIRA DE ANDRADE, MIRELLA CRISTINY; DA FONSECA, DENISE MORAIS; BASSO, PAULO JOSE; SARAIVA CAMARA, NIELS OLSEN; DE SALES E SOUZA, ERICKA LORENNA; et al. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism. CELL REPORTS, v. 27, n. 3, p. 750+, APR 16 2019. Web of Science Citations: 3. (16/23142-3, 17/06577-9, 12/10653-9, 17/01451-7, 17/16280-3, 14/03002-7, 13/06810-4, 18/02208-1, 17/25679-7, 17/26366-2, 15/06134-4, 18/01753-6, 15/01507-7)
RODRIGUES, HOSANA G.; SATO, FABIO TAKEO; CURI, RUI; VINOLO, MARCO A. R.. Fatty acids as modulators of neutrophil recruitment, function and survival. European Journal of Pharmacology, v. 785, p. 50-58, AUG 15 2016. Web of Science Citations: 20. (12/15774-9, 12/10653-9, 13/06810-4)
RODRIGUES, HOSANA G.; VINOLO, MARCO A. R.; SATO, FABIO T.; MAGDALON, JULIANA; KUHL, CAROLINA M. C.; YAMAGATA, ANA S.; PESSOA, ANA FLAVIA M.; MALHEIROS, GABRIELLA; DOS SANTOS, MARINILCE F.; LIMA, CAMILA; et al. Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats. PLoS One, v. 11, n. 10, OCT 20 2016. Web of Science Citations: 8. (12/10653-9, 13/06810-4)
SILVA, JESSICA R.; BURGER, BEATRIZ; KUHL, CAROLINA M. C.; CANDREVA, THAMIRIS; DOS ANJOS, MARIAH B. P.; RODRIGUES, HOSANA G.. Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair. Mediators of Inflammation, 2018. Web of Science Citations: 6. (13/06810-4)
CANDREVA, THAMIRIS; KUHL, CAROLINA M. C.; BURGER, BEATRIZ; DOS ANJOS, MARIAH B. P.; TORSONI, MARCIO A.; CONSONNI, SILVIO R.; CRISMA, AMANDA R.; FISK, HELENA L.; CALDER, PHILIP C.; DE MATO, FELIPE C. P.; et al. Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue. Clinical Science, v. 133, n. 22, p. 2345-2360, NOV 2019. Web of Science Citations: 0. (14/15127-9, 13/06810-4, 16/02021-3, 16/23298-3)
(References retrieved automatically from State of São Paulo Research Institutions)
BURGER, Beatriz. Efeitos da suplementação com ácido graxo ômega-3 eicosapentaenoico (EPA) na cicatrização de feridas em camundongos diabéticos : Effects of eicosapentaenoic (EPA) omega-3 fatty acid supplementation on wound healing in diabetic mice . Dissertação (Mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Aplicadas. (18/00529-5)
RODRIGUES, Hosana Gomes. Modulação do processo de cicatrização pelos ácidos oleico e linoleico.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (07/52766-6)
ROBLES, Thamiris Candreva. Cicatrização de feridas em camundongos FAT-1 = envolvimento da via anti-inflamatória colinérgica = Wound healing in FAT-1 mice: involvement of the cholinergic anti-inflammatory pathway. Dissertação (Mestrado) - Faculdade de Ciências Aplicadas (FCA). Universidade Estadual de Campinas (UNICAMP). (16/02021-3)
SILVA, Jessica Rondoni. Ácido graxo linoleico e cicatrização de feridas : enfoque na angiogênese = Linoleic fatty acid and wound healing: focus on angiogenesis. Dissertação (Mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Aplicadas. (16/15955-4)