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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1,4-disubstituted-1,2,3-triazoles

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Ali, Akbar [1] ; Correa, Arlene G. [1] ; Alves, Diego [2] ; Zukerman-Schpector, Julio [1] ; Westermann, Bernhard [3] ; Ferreira, Marco A. B. [1] ; Paixao, Marcio W. [1]
Total Authors: 7
[1] Univ Fed Sao Carlos UFSCar, Dept Chem, Sao Carlos, SP - Brazil
[2] Univ Fed Pelotas UFPel, Dept Chem, Pelotas, RS - Brazil
[3] Leibniz Inst Plant Biochem, Dept Bioorgan Chem, Halle - Germany
Total Affiliations: 3
Document type: Journal article
Source: CHEMICAL COMMUNICATIONS; v. 50, n. 80, p. 11926-11929, 2014.
Web of Science Citations: 47

A simple and efficient metal-free methodology for the regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles has been developed by applying a novel inverse electron-demand-1,3-dipolar cycloaddition approach. The practical one-pot metal-free strategy can be accomplished with various alkylidene malononitriles and aromatic azides in the presence of base. (AU)

FAPESP's process: 09/54040-8 - Acquisition of a high-resolution Orbitrap mass spectrometer for the discovery and structural analysis of biologically active compounds: applications in proteomics, biomarkers, synthesis, isolation, and characterization of natural products, studies of redox systems in food and enzymatic synthesis
Grantee:Emanuel Carrilho
Support type: Multi-user Equipment Program
FAPESP's process: 09/07281-0 - Asymmetric organocatalysis: design of new organocatalysts and development of new methodologies
Grantee:Márcio Weber Paixão
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 13/02311-3 - New approaches in asymmetric synthesis of tetrahydrofuran and tetrahydropyran-derivatives with potential application in the preparation of bioactive molecules
Grantee:Marco Antonio Barbosa Ferreira
Support type: Regular Research Grants