Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1,4-disubstituted-1,2,3-triazoles

Full text
Author(s):
Ali, Akbar [1] ; Correa, Arlene G. [1] ; Alves, Diego [2] ; Zukerman-Schpector, Julio [1] ; Westermann, Bernhard [3] ; Ferreira, Marco A. B. [1] ; Paixao, Marcio W. [1]
Total Authors: 7
Affiliation:
[1] Univ Fed Sao Carlos UFSCar, Dept Chem, Sao Carlos, SP - Brazil
[2] Univ Fed Pelotas UFPel, Dept Chem, Pelotas, RS - Brazil
[3] Leibniz Inst Plant Biochem, Dept Bioorgan Chem, Halle - Germany
Total Affiliations: 3
Document type: Journal article
Source: CHEMICAL COMMUNICATIONS; v. 50, n. 80, p. 11926-11929, 2014.
Web of Science Citations: 47
Abstract

A simple and efficient metal-free methodology for the regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles has been developed by applying a novel inverse electron-demand-1,3-dipolar cycloaddition approach. The practical one-pot metal-free strategy can be accomplished with various alkylidene malononitriles and aromatic azides in the presence of base. (AU)

FAPESP's process: 09/54040-8 - Acquisition of a high-resolution Orbitrap mass spectrometer for the discovery and structural analysis of biologically active compounds: applications in proteomics, biomarkers, synthesis, isolation, and characterization of natural products, studies of redox systems in food and enzymatic synthesis
Grantee:Emanuel Carrilho
Support type: Multi-user Equipment Program
FAPESP's process: 09/07281-0 - Asymmetric organocatalysis: design of new organocatalysts and development of new methodologies
Grantee:Márcio Weber Paixão
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 13/02311-3 - New approaches in asymmetric synthesis of tetrahydrofuran and tetrahydropyran-derivatives with potential application in the preparation of bioactive molecules
Grantee:Marco Antonio Barbosa Ferreira
Support type: Regular Research Grants