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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Fluid bed drying and agglomeration of phytopharmaceutical compositions

Full text
Author(s):
Benelli, Lucimara [1] ; Cortes-Rojas, Diego F. [1] ; Souza, Claudia Regina F. [1] ; Oliveira, Wanderley Pereira [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Powder Technology; v. 273, p. 145-153, MAR 2015.
Web of Science Citations: 5
Abstract

This work aims to investigate the feasibility of fluidised beds for seed agglomeration of rosemary (Rosmarinus officinalis) extract compositions, attempting to form a product with adequate pharmacotechnical and physicochemical properties. Lipid- and carbohydrate-based compositions with different viscosities were top sprayed onto fluidised beds of cassava flour or sugar pellets as seed particles. The compositions used were also spray-dried to compare the physicochemical properties of the product generated by the two processes. The viscosity of the feed formulations influenced the efficiency of the coating/agglomeration and the agglomeration percentage of the granules. Fluidised bed granules exhibited higher efficiency of coating/agglomeration, higher retention of bioactive compounds and better flow properties than the powder obtained by spray drying. (C) 2014 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 12/09890-6 - Encapsulation of bioactive compounds from Syzygium aromaticum in solid lipidic carriers
Grantee:Diego Francisco Cortés-Rojas
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 12/03427-2 - Microencapsulation and nanoencapsulation of natural compounds by drying technologies
Grantee:Cláudia Regina Fernandes de Souza
Support Opportunities: Scholarships in Brazil - Young Researchers
FAPESP's process: 11/10333-1 - Microencapsulation and nanoencapsulation of natural compounds by drying technologies
Grantee:Cláudia Regina Fernandes de Souza
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 12/00562-6 - Fluidized bed encapsulation of herbal extracts
Grantee:Lucimara Benelli
Support Opportunities: Scholarships in Brazil - Doctorate