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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Optical paper-based sensor for ascorbic acid quantification using silver nanoparticles

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Author(s):
Melo Ferreira, Danielle Cristhina [1] ; Giordano, Gabriela Furlan [1] ; dos Santos Penteado Soares, Caio Cesar [1] ; Afonso de Oliveira, Jessica Fernanda [2, 3] ; Mendes, Renata Kelly [4] ; Piazzetta, Maria Helena [1] ; Gobbi, Angelo Luiz [1] ; Cardoso, Mateus Borba [2, 3]
Total Authors: 8
Affiliation:
[1] Ctr Nacl Pesquisa Energia & Mat, LNNano Lab Nacl Nanotecnol, BR-13083970 Sao Paulo - Brazil
[2] Univ Estadual Campinas, Inst Quim, BR-13083970 Sao Paulo - Brazil
[3] Ctr Nacl Pesquisa Energia & Mat, LNLS, BR-13083970 Sao Paulo - Brazil
[4] Pontificia Univ Catolica Campinas, Fac Quim, BR-13012970 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Talanta; v. 141, p. 188-194, AUG 15 2015.
Web of Science Citations: 34
Abstract

In this paper, we demonstrate for the first time the use of silver nanoparticles (AgNPs) for colorimetric ascorbic acid (AA) quantification in a paper-based sensor. This device is constituted by spot tests modified with AgNPs and silver ions bordered by a hydrophobic barrier which provides quantitative and fast analysis of AA. In addition, this device is employed as point-of-care monitoring using a unique drop of the sample. AgNPs paper-based sensor changed from light yellow to gray color after the addition of AA due to nanoparticle growth and clusters formation. The color intensities were altered as a function of AA concentration which were measured by either a scanner or a homemade portable transmittance colorimeter. Under the selected measurement conditions, results presented limit of detection which was comparable to analytical laboratory-based methodologies. In addition, the sensitivity of our sensor was comparable to the standard titration method when real samples were investigated. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 11/21954-7 - Functionalization of composite nanoparticles for biomedical applications
Grantee:Mateus Borba Cardoso
Support Opportunities: Regular Research Grants
FAPESP's process: 13/22429-9 - Synthesis of mesoporous silica nanoparticles functionalized with monoclonal antibodies: an alternative to Hodgkin (HL) and anaplastic large cell CD30+ (ALCL - CD30+) lymphomas treatment
Grantee:Jessica Fernanda Affonso de Oliveira
Support Opportunities: Scholarships in Brazil - Doctorate