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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

High frequency of deficient consumption and low blood levels of 25-hydroxyvitamin D in HIV-1-infected adults from Sao Paulo city, Brazil

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Author(s):
Sales, Stephanie Hael [1] ; da Matta, Sandra [1] ; da Silva, Daniela Cardeal [2] ; Assone, Tatiane [2] ; Fonseca, Luiz Augusto M. [3] ; Duarte, Alberto J. S. [1] ; Casseb, Jorge [2, 1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Sch Med, Dept Dermatol, Lab Dermatol & Immunedeficiencies, Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Trop Med, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Dept Prevent Med, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 5, AUG 10 2015.
Web of Science Citations: 4
Abstract

Micronutrient deficiency is common in patients with HIV/AIDS, usually caused by mal-absorption and/or drug interactions. 25-hydroxyvitamin D is of fundamental importance for the homeostasis of musculoskeletal health. The current study aimed to evaluate the nutritional status of HIV-infected subjects in order to make their nutritional diagnoses, including their vitamin D blood levels, and to estimate their consumption of vitamin D. The study included 98 HIV-1-infected subjects, followed at University of Sao Paulo Medical School -HC-FMUSP. We performed a nutritional evaluation, along with the determination of patients' serum 25-hydroxyvitamin D and calcium concentration, biochemical analyses, and an anthropometric assessment. In the medical interview a 24-hour food recall was used (R24) to estimate daily calorie intake, macronutrients, calcium, and vitamin D. A high level of vitamin D deficiency was observed in our patients: 83.4% of them had levels below 30 ng/ml; they also presented an increased risk of cardiovascular disease, along with a high consumption of dietary fat. Factors related to the virus itself and to the use of antiretroviral drugs may have contributed for the low vitamin D levels seen in our HIV-1-infected patients. (AU)

FAPESP's process: 11/04868-0 - PREVALENCE OF ABSORPTION AND DEFICIENCY OF VITAMIN D AND CALCIUM IN PATIENTS LIVING WITH HIV / AIDS
Grantee:Stephanie Bianca Haél Sales
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 15/12311-6 - High frequency of deficient consumption and low blood levels of 25-hydroxyvitamin D in HIV-1-infected adults from São Paulo city, Brazil
Grantee:Jorge Simao do Rosario Casseb
Support Opportunities: Regular Research Grants - Publications - Scientific article