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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Structural characterization of beta-carotene-incorporated nanovesicles produced with non-purified phospholipids

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Author(s):
Michelon, Mariano [1] ; Mantovani, Raphaela Araujo [1] ; Sinigaglia-Coimbra, Rita [2] ; de la Torre, Lucimara Gaziola [3] ; Cunha, Rosiane Lopes [1]
Total Authors: 5
Affiliation:
[1] Univ Campinas UNICAMP, Fac Food Engn, Dept Food Engn, BR-13083862 Campinas, SP - Brazil
[2] Fed Univ Sao Paulo UNIFESP, Paulista Sch Med, Ctr Electron Microscopy, BR-04023062 Sao Paulo, SP - Brazil
[3] Univ Campinas UNICAMP, Fac Chem Engn, Dept Mat & Bioproc Engn, BR-13083852 Campinas, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Food Research International; v. 79, p. 95-105, JAN 2016.
Web of Science Citations: 15
Abstract

The technical feasibility of obtaining beta-carotene-incorporated phospholipid nanovesicles using non-purified soybean lecithins was studied. For this purpose, three lecithin-types were evaluated. Nanovesicles were characterized by average hydrodynamic diameter, particle size distribution, polydispersity index, zeta-potential, transmission electron microscopy, membrane microviscosity, small angle X-ray scattering and capacity of lipid peroxidation inhibition. In general, the beta-carotene incorporation did not promote a significant increase on average hydrodynamic diameter, but vesicles produced from lecithins containing triglycerides showed lower polydispersity. The lecithin type used to produce nanovesicles did not influence the beta-carotene loading capacity, but significantly influenced the microviscosity of liposomal membrane and lipid peroxidation inhibition capacity. Non-enzymatically modified lecithin (containing or not triglycerides) showed similar efficiency and peroxidation inhibition capacity considering beta-carotene incorporation. Therefore, low-cost non-purified lecithin can be employed for production of liposomal systems as an encapsulating and/or delivery system to be used in food products. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 09/54137-1 - Acquisition of a particle size/distribution analyzer, a zeta potential measurement system, a spray dryer, and an ultra-high-pressure liquid chromatograph/mass spectrometer
Grantee:Miriam Dupas Hubinger
Support Opportunities: Multi-user Equipment Program