| Full text | |
| Author(s): |
Total Authors: 3
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| Affiliation: | [1] Hosp Israelita Albert Einstein, Sao Paulo - Brazil
[2] Univ Sao Paulo, Bioinformat Interunits Grad Program, Sao Paulo - Brazil
[3] Univ Estadual Paulista, Inst Fis Teor, Rua Pamplona 145, BR-01405 Sao Paulo - Brazil
Total Affiliations: 3
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| Document type: | Journal article |
| Source: | European Physical Journal-Special Topics; v. 225, n. 1, p. 75-82, FEB 2016. |
| Web of Science Citations: | 3 |
| Abstract | |
In this work, we propose changes in the structure of a neuronal network with the intention to provoke strong synchronization to simulate episodes of epileptic seizure. Starting with a network of Izhikevich neurons we slowly increase the number of connections in selected nodes in a controlled way, to produce (or not) hubs. We study how these structures alter the synchronization on the spike firings interval, on individual neurons as well as on mean values, as a function of the concentration of connections for random and non-random (hubs) distribution. We also analyze how the post-ictal signal varies for the different distributions. We conclude that a network with hubs is more appropriate to represent an epileptic state. (AU) | |
| FAPESP's process: | 11/11973-4 - ICTP South American Institute for Fundamental Research: a regional center for theoretical physics |
| Grantee: | Nathan Jacob Berkovits |
| Support Opportunities: | Research Projects - Thematic Grants |