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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

BINARY, TERNARY AND QUATERNARY INCLUSION COMPLEXES CONTAINING Lippia sidoides ESSENTIAL OIL

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Author(s):
Cláudia R. F. Souza [1] ; Patrícia N. Ferraz-Freitas [2] ; Wanderley P. Oliveira [3]
Total Authors: 3
Affiliation:
[1] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Ciências Farmacêuticas - Brasil
[2] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Ciências Farmacêuticas - Brasil
[3] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Ciências Farmacêuticas - Brasil
Total Affiliations: 3
Document type: Journal article
Source: Química Nova; v. 39, n. 8, p. 979-986, 2016-09-00.
Abstract

The aim of this work was the production and characterization of binary, ternary and quaternary complexes based on β-cyclodextrin (β-CD) and Lippia sidoides essential oil (EO). OE:β-CD formulations at proportions of 1:10 to 2:10 (binary); added with surfactant or polymer (ternary) or with both (quaternary) were prepared and submitted to spray drying at optimized operating conditions (inlet gas temperature: 160 °C, drying gas flow rate: 60 m3/h; feed flow rate: 4 g/min; pressure and flow rate of the atomizing air: 2.5 kgf/cm2 and 17 lpm). The responses evaluated were the encapsulation efficiency (EE), powder properties, product morphology, and process efficiency (REC). The results showed that the addition of polymer and surfactant to β-CD, generating ternary and quaternary complexes improved the encapsulation efficiency, drying yield, and modify the particles morphology. Samples with lower EO: β-CD ratio (1:10) showed high encapsulation efficiency. (AU)

FAPESP's process: 14/15905-1 - Encapsulation of essential oils in solid lipid carriers: technological development and applications
Grantee:Wanderley Pereira Oliveira
Support Opportunities: Regular Research Grants
FAPESP's process: 11/10333-1 - Microencapsulation and nanoencapsulation of natural compounds by drying technologies
Grantee:Cláudia Regina Fernandes de Souza
Support Opportunities: Research Grants - Young Investigators Grants