Association between Polyphenol Intake and Hyperten... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Association between Polyphenol Intake and Hypertension in Adults and Older Adults: A Population-Based Study in Brazil

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Author(s):
Miranda, Andreia Machado ; Steluti, Josiane ; Fisberg, Regina Mara ; Marchioni, Dirce Maria
Total Authors: 4
Document type: Journal article
Source: PLoS One; v. 11, n. 10 OCT 28 2016.
Web of Science Citations: 23
Abstract

Background/Objective Hypertension is an important risk factor for cardiovascular disease, and diet has been identified as a modifiable factor for preventing and controlling hypertension. Besides, epidemiological studies have suggested an inverse association between polyphenol intake and cardiovascular diseases. The aim of this study was to evaluate the association between the intake of polyphenols and hypertension in a general population of Sao Paulo. Methods Data came from the `Health Survey of Sao Paulo (ISA-Capital)' among 550 adults and older adults in Sao Paulo, Brazil. Diet was assessed by two 24-hour dietary recalls (24HR). Usual intakes were calculated using the Multiple Source Method. Polyphenol intake was calculated by matching food consumption data from the 24HR with the Phenol-Explorer database. The associations between the hypertension and tertiles of the total and classes of polyphenols intake were tested by multivariate logistic regression analysis. Results After multivariate adjustment for potential confounding factors the findings showed an inverse and linearly association between the hypertension and highest tertiles of tyrosols (OR = 0.33; 95% CI 0.18, 0.64), alkylphenols (OR = 0.45; 95% CI 0.23, 0.87), lignans (OR = 0.49; 95% CI 0.25, 0.98), as well as stilbenes (OR = 0.60; 95% CI 0.36, 0.98), and other polyphenols (OR = 0.33; 95% CI 0.14, 0.74). However, total polyphenol intake, and phenolic acids were significantly associated only in the middle tertile with hypertension and flavonoids were not significant associated. Conclusion There is an inverse and linearly association between the highest tertile of some classes of polyphenols, such as, tyrosols, alkylphenols, lignans, stilbenes, other polyphenols and hypertension. (AU)

FAPESP's process: 14/04540-2 - Epidemiological study of coffee consumption, its contribution for polyphenols intake and potential effects on cardiovascular risk factors, considering individual genetic variations
Grantee:Andreia Alexandra Machado Miranda
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 09/15831-0 - Dietary factors, homocystein, MTHFR gene polymorphisms, and cardiovascular risk in adults and the elderly: a population-based study - ISA - Capital
Grantee:Regina Mara Fisberg
Support Opportunities: Regular Research Grants